Gibco™ Human Plateable Hepatocytes, Transporter Qualified

Human Plateable Hepatocytes, Transporter Qualified

Supplier:  Gibco™ HMCPTS

Catalog No. HMCPTS

Description

Plateable cryopreserved human hepatocytes assessed for transporter function using uptake transporter assays at both 4°C and 37°C.

Cells per vial: 4-8 million

Hepatocyte cultures were incubated with radiolabeled taurocholate, digoxin, and estradiol 17β glucuronide (E2-17G), substrates of the uptake and efflux transporters NTCP and BSEP, OCT1 and MDR1, and OATPs and MRP2, respectively. Accumulation rates and biliary excretion index (BEI%) were calculated.

Get the Results You Need with GIBCO Hepatocytes
High quality hepatocytes, with high viabilities, in vivo-like enzyme expression levels, and proper cell morphology increase the ability to draw in vitro⁄in vivo correlations and make sound decisions regarding a compound's fate. Experienced technicians and proprietary isolation techniques combined with stringent release specifications ensure you receive the highest quality cryopreserved hepatocytes.

Each lot is tested for:

Phase I and II enzyme activities

Proper morphology

Viabilities generally >75%

Attachment efficiency

Monolayer formation and integrity

For research use only. Not intended for human or animal therapeutic or diagnostic use.

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Note:
These products require shipment in LN₂ vapor dewars therefore additional fees may apply.

Specifications

• Content And Storage: Store in a cryostorage dewar or -135°C freezer.
• Culture Type: Hepatocyte Cell Culture
• Species: Human
• No. of Cells: 4-8 x 10^6
• Product Type: Hepatocytes

• Cell Type: Hepatocytes
• Form: Cryopreserved
• Donor Source: Single Donor
• Product Line: Gibco™
• Quantity: 1 vial

For Research Use Only. Not for use in diagnostic procedures.