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Gibco™ Human Plateable Hepatocytes, Induction Qualified

Human Plateable Hepatocytes, Induction Qualified

Supplier:  Gibco™ HMCPIS

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Catalog No. HMCPIS


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Description

Description

These plateable cryopreserved human hepatocytes are inducible and suitable for use in experiments monitoring in vitro enzyme induction.

Cells per vial: 4-8 million

The potentials of known clinically relevant enzyme inducers represented by 3-methylcholanthrene (3-MC, a prototypical CYP1A enzyme inducer, 3μM), phenobarbital (PB, a prototypical CYP2B inducer, 1000μM) and rifampicin (RIF, a prototypical CYP3A enzyme inducer, 10μM) have been assessed to verify that each lot is inducible.

Get the Results You Need with GIBCO Hepatocytes
High quality hepatocytes, with high viabilities, in vivo-like enzyme expression levels, and proper cell morphology increase the ability to draw in vitro/in vivo correlations and make sound decisions regarding a compound's fate. Experienced technicians and proprietary isolation techniques combined with stringent release specifications ensure you receive the highest quality cryopreserved hepatocytes.

Each lot is tested for:
  • Phase I and II enzyme activities
  • Proper morphology
  • Viabilities generally >75%
  • Attachment efficiency
  • Monolayer formation and integrity

    For research use only. Not intended for human or animal therapeutic or diagnostic use.

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  • Specifications

    Specifications

    Store in a cryostorage dewar or -135°C freezer.
    Mammalian Cell Culture
    Human
    4-8 x 10^6
    Hepatocytes
    Hepatocytes
    Cryopreserved
    Single Donor
    Gibco™
    1 vial
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    For Research Use Only. Not for use in diagnostic procedures.