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Hemin Chloride, MP Biomedicals™

Catalog Number MP21988202
Click to view available options
Quantity:
250 mg
16009-13-5
C34H32FeN4O4
616.50
MFCD00010726
GGIDWJQWCUJYRY-UHFFFAOYSA-L
chlorohemin, hemin chloride, protoferriheme, ferriheme, ferriprotoporphyrin ix chloride, ferriprotoporphyrin ix, panhematin, protohemin, protohemin ix, ferriprotoporphyrin
131675604
iron(3+) 4,20-bis(2-carboxyethyl)-9,14-diethenyl-5,10,15,19-tetramethyl-21,22,23,24-tetraazapentacyclo[16.2.1.1³,⁶.1⁸,¹¹.1¹³,¹⁶]tetracosa-1(20),2,4,6(24),7,9,11,13(22),14,16,18-undecaene-21,23-diide
[Fe+3].CC1=C2[N-]C(C=C3N=C(C=C4[N-]C(=CC5=NC(=C2)C(C)=C5C=C)C(C)=C4C=C)C(C)=C3CCC(O)=O)=C1CCC(O)=O
16009-13-5
C34H32FeN4O4
616.50
MFCD00010726
GGIDWJQWCUJYRY-UHFFFAOYSA-L
chlorohemin, hemin chloride, protoferriheme, ferriheme, ferriprotoporphyrin ix chloride, ferriprotoporphyrin ix, panhematin, protohemin, protohemin ix, ferriprotoporphyrin
131675604
iron(3+) 4,20-bis(2-carboxyethyl)-9,14-diethenyl-5,10,15,19-tetramethyl-21,22,23,24-tetraazapentacyclo[16.2.1.1³,⁶.1⁸,¹¹.1¹³,¹⁶]tetracosa-1(20),2,4,6(24),7,9,11,13(22),14,16,18-undecaene-21,23-diide
[Fe+3].CC1=C2[N-]C(C=C3N=C(C=C4[N-]C(=CC5=NC(=C2)C(C)=C5C=C)C(C)=C4C=C)C(C)=C3CCC(O)=O)=C1CCC(O)=O

Description

Used to study bacterial strains and growth conditions. Hemin Chloride, MP Biomedicals is the oxidized version of heme. It is an iron-containing porphyrin, a prosthetic group for a diverse group of proteins. Free heme is pro-inflammatory and contributes to

Hemin is a Protoporphyrin IX containing a ferric iron ion (Heme B) with a chloride ligand. It is the oxidized version of heme. Free heme can be released from hemoglobin following hemolysis. Free hemin levels may be upregulated in various pathological conditions and can contribute to various inflammatory conditions including vascular disorders, renal failure, and immune-mediated disorders.

Hemin is used for studying bacterial strains and growth conditions, cell transfections, and short-term colony assays (the culture medium consists of hemin along with other components). It is used in β-hematin formation assay for analyzing the inhibitory activity of MMV (Medicines for Malaria Venture) Malaria Box compounds against the formation of β-hematin. It may also be used to study the expression, represson and activity of heme oxygenase 1 (HO-1). Hematin is the “X factor” required to grown Haemophilus influenzae.

Melting Point 2735°C (1013hPa (literature))
Quantity 250 mg
Formula Weight 652g/mol
Physical Form Powder

Safety and Handling

Recommended Storage Store at 4°C, protect from light.
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