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  7. Guanidine hydrochloride, 98%, Thermo Scientific Chemicals

Guanidine hydrochloride, 98%, Thermo Scientific Chemicals

Catalog Number AAA135430B
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Quantity:
250 g
1000 g
5000 g
50-01-1
CH6ClN3
95.53
MFCD00013026
PJJJBBJSCAKJQF-UHFFFAOYSA-N
guanidine hydrochloride, guanidinium chloride, guanidine, monohydrochloride, aminoformamidine hydrochloride, aminomethanamidine hydrochloride, guanidine monohydrochloride, guanidine hcl, guanidine chloride, iminourea hydrochloride, carbamidine hydrochloride
5742
CHEBI:32735
guanidine;hydrochloride
C(=N)(N)N.Cl
50-01-1
CH6ClN3
95.53
MFCD00013026
PJJJBBJSCAKJQF-UHFFFAOYSA-N
guanidine hydrochloride, guanidinium chloride, guanidine, monohydrochloride, aminoformamidine hydrochloride, aminomethanamidine hydrochloride, guanidine monohydrochloride, guanidine hcl, guanidine chloride, iminourea hydrochloride, carbamidine hydrochloride
5742
CHEBI:32735
guanidine;hydrochloride
C(=N)(N)N.Cl

Description

Guanidine hydrochloride, CAS # 50-01-1, is an ionic buffer component used for nucleic acids (DNA and RNA) and protein isolation.

Guanidine hydrochloride is used for purification of proteins and nucleic acids. It can be used as a medicine, organic synthesis intermediate and is used in dyes. It acts as an intermediate in the preparation of sulfadiazine, which is an important raw material for sulfamethyldiazine, sulfamethazine and folic acid. It is utilized in the synthesis of 2-amino-pyrimidine, 2- amino -6- methyl-pyrimidine and 2-amino -4,6 - dimethyl-pyrimidine. Also used in RNA isolation to dissociate nucleoproteins and inhibit RNase.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

  • Guanidine hydrochloride is the hydrochloride salt of guanidine, an acetylcholine releasing agent
  • It is a normal product of protein metabolism and is sometimes used for pyrimidine synthesis

Application

  • Guanidine hydrochloride is a powerful denaturant, useful for taking nucleic acids (DNA and RNA) and proteins out of their native conformation
  • Guanidine hydrochloride acts as a strong organic base at physiological pH
  • It is suitable for use in protein and nucleic acid purification protocols
TRUSTED_SUSTAINABILITY
Melting Point 178°C to 185°C
Density 1.344
Quantity 1000 g
Beilstein 3591990
Sensitivity Hygroscopic
Merck Index 144562
Solubility Information Soluble in water and ethanol.
Formula Weight 95.53
Percent Purity 98%
Chemical Name or Material Guanidine hydrochloride

Safety and Handling

Hazard Category Serious eye damage/eye irritation (category 2), Skin corrosion/irritation (category 2), Acute toxicity (category 4)
Hazard Statement Causes serious eye irritation, May form combustible dust concentrations in air, Causes skin irritation, Harmful if swallowed or if inhaled
EINECSNumber 200-002-3
RTECSNumber MF4300000
TSCA Yes
Recommended Storage Ambient temperatures
SDS

RUO – Research Use Only

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