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  8. GSK 269962, Tocris Bioscience™ 

GSK 269962, Tocris Bioscience™

Catalog Number 400950
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
850664-21-0
C29H30N8O5
570.61
YOVNFNXUCOWYSG-UHFFFAOYSA-N
aminofurazanyl-azabenzimidazole 6n, n-3-2-4-amino-1,2,5-oxadiazol-3-yl-1-ethyl-1h-imidazo 4,5-c pyridin-6-yl oxy phenyl-4-2-morpholin-4-yl ethoxy benzamide, kinome_3843, d02zqs, n-3-2-4-amino-1,2,5-oxadiazol-3-yl-1-ethyl-1h-imidazo 4,5-c pyridin-6-yl oxy phenyl-4-2-4-morpholinyl ethoxy benzamide, n-3-2-4-amino-furazan-3-yl-1-ethyl-1h-imidazo 4,5-c pyridin-6-yl oxy phenyl-4-2-4-morpholinyl ethyl oxy benzamide, n-3-2-4-amino-1,2,5-oxadiazol-3-yl-1-ethylimidazo 5,4-d pyridin-6-yl oxyphenyl-4-2-morpholin-4-ylethoxy benzamide
16095342
N-[3-[2-(4-amino-1,2,5-oxadiazol-3-yl)-1-ethylimidazo[4,5-c]pyridin-6-yl]oxyphenyl]-4-(2-morpholin-4-ylethoxy)benzamide
CCN1C2=CC(=NC=C2N=C1C3=NON=C3N)OC4=CC=CC(=C4)NC(=O)C5=CC=C(C=C5)OCCN6CCOCC6
This item is not returnable. View return policy
850664-21-0
C29H30N8O5
570.61
YOVNFNXUCOWYSG-UHFFFAOYSA-N
aminofurazanyl-azabenzimidazole 6n, n-3-2-4-amino-1,2,5-oxadiazol-3-yl-1-ethyl-1h-imidazo 4,5-c pyridin-6-yl oxy phenyl-4-2-morpholin-4-yl ethoxy benzamide, kinome_3843, d02zqs, n-3-2-4-amino-1,2,5-oxadiazol-3-yl-1-ethyl-1h-imidazo 4,5-c pyridin-6-yl oxy phenyl-4-2-4-morpholinyl ethoxy benzamide, n-3-2-4-amino-furazan-3-yl-1-ethyl-1h-imidazo 4,5-c pyridin-6-yl oxy phenyl-4-2-4-morpholinyl ethyl oxy benzamide, n-3-2-4-amino-1,2,5-oxadiazol-3-yl-1-ethylimidazo 5,4-d pyridin-6-yl oxyphenyl-4-2-morpholin-4-ylethoxy benzamide
16095342
N-[3-[2-(4-amino-1,2,5-oxadiazol-3-yl)-1-ethylimidazo[4,5-c]pyridin-6-yl]oxyphenyl]-4-(2-morpholin-4-ylethoxy)benzamide
CCN1C2=CC(=NC=C2N=C1C3=NON=C3N)OC4=CC=CC(=C4)NC(=O)C5=CC=C(C=C5)OCCN6CCOCC6

Description

Potent and selective ROCK inhibitor

Potent Rho kinase (ROCK) inhibitor (IC50 values are 1.6 and 4 nM for recombinant human ROCK1 and ROCK2 respectively). Displays greater than 30-fold selectivity for ROCK against a panel of serine/threonine kinases. Induces vasorelaxation in preconstricted rat aorta (IC50 = 35 nM); lowers blood pressure in a rat model of hypertension.
Quantity 50 mg
Formula Weight 570.6
Percent Purity >99%
Chemical Name or Material GSK 269962

Safety and Handling

Recommended Storage Store at +4°C
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