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  6. Gemcitabine hydrochloride, Tocris Bioscience™

Gemcitabine hydrochloride, Tocris Bioscience™

Catalog Number 325950
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
122111-03-9
C9H12ClF2N3O4
299.659
OKKDEIYWILRZIA-OSZBKLCCSA-N
gemcitabine hcl, 2',2'-difluorodeoxycytidine monohydrochloride, 2'-deoxy-2',2'-difluorocytidine hydrochloride, 2 1h-pyrimidinone, 4-amino-1-2-deoxy-2,2-difluoro-d-erythro-pentofuranosyl
44558863
CHEBI:31647
4-amino-1-[(2R,4R,5R)-3,3-difluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one;hydron;chloride
[H+].C1=CN(C(=O)N=C1N)C2C(C(C(O2)CO)O)(F)F.[Cl-]
This item is not returnable. View return policy
122111-03-9
C9H12ClF2N3O4
299.659
OKKDEIYWILRZIA-OSZBKLCCSA-N
gemcitabine hcl, 2',2'-difluorodeoxycytidine monohydrochloride, 2'-deoxy-2',2'-difluorocytidine hydrochloride, 2 1h-pyrimidinone, 4-amino-1-2-deoxy-2,2-difluoro-d-erythro-pentofuranosyl
44558863
CHEBI:31647
4-amino-1-[(2R,4R,5R)-3,3-difluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one;hydron;chloride
[H+].C1=CN(C(=O)N=C1N)C2C(C(C(O2)CO)O)(F)F.[Cl-]

Description

DNA synthesis inhibitor

Deoxycytidine analog that inhibits DNA synthesis. Metabolized to form gemcitabine triphosphate (dFdCTP) and gemcitabine diphosphate (dFdCDP). dFdCTD inhibits ribonucleotide reductase causing a reduction in cellular nucleotides. dFdCTP is incorporated in DNA resulting in DNA strand termination. Displays antitumor activity in vitro and in vivo.
Quantity 50 mg
Formula Weight 299.66
Percent Purity >99%
Chemical Name or Material Gemcitabine hydrochloride

Safety and Handling

Recommended Storage Desiccate at +4°C
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