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Gabexate mesylate, Tocris Bioscience™
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Quantity:
10 mg
50 mg
Description
Gabexate mesylate is a serine protease inhibitor; Gabexate mesylate inhibits trypsin, plasmin, plasma kallikrein and thrombin (IC50 values are 9.4, 30, 41 and 110 μM respectively). Antithrombotic in vitro and in vivo. Gabexate mesylate also inhibits LPS-induced TNF-α production, probably by inhibiting NF-κB and AP-1 activation. Gabexate mesylate attenuates allergen-induced airway inflammation and eosinophils infiltration in the lung of asthma murine model.
Specifications
Quantity | 50 mg |
Formula Weight | 417.48 |
Percent Purity | >98% |
Chemical Name or Material | Gabexate mesylate |
Safety and Handling
Recommended Storage | Desiccate at Room Temperature |
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