Ethoxyacetylene, ca 50% w/w in hexanes, Thermo Scientific Chemicals

Description

Ethoxyacetylene is used in Arens-van Dorp synthesis to prepare propargyl alcohol via reaction with ketone. In organic synthesis, it undergoes [2+2] cycloaddition reactions with ketenes to give cyclobutenone derivatives. It is also used to prepare alpha, beta-unsaturated esters from ketones by following Meyer-Schuster rearrangement.Used with N-vinylamides and triflic anhydride in a direct, three-component synthesis of pyridines. Also used to prepare α, β-unsaturated esters from ketones via a Meyer-Schuster rearrangement.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Ethoxyacetylene is used in Arens-van Dorp synthesis to prepare propargyl alcohol via reaction with ketone. In organic synthesis, it undergoes [2+2] cycloaddition reactions with ketenes to give cyclobutenone derivatives. It is also used to prepare alpha, beta-unsaturated esters from ketones by following Meyer-Schuster rearrangement.Used with N-vinylamides and triflic anhydride in a direct, three-component synthesis of pyridines. Also used to prepare α, β-unsaturated esters from ketones via a Meyer-Schuster rearrangement.

Solubility
Slightly miscible with water.

Notes
Incompatible with strong oxidizing agents and strong acids.

Specifications

• Density: 0.718
• Boiling Point: 55°C to 56°C
• Flash Point: −28°C (−18°F)
• Odor: Recognizable
• Refractive Index: 1.38
• Linear Formula: CH₃CH₂OC≡CH
• Quantity: 5 g
• UN Number: UN1993
• Beilstein: 741882
• Solubility Information: Slightly miscible with water.
• Formula Weight: 70.09
• Concentration or Composition (by Analyte or Components): ≈50% w/w in hexanes
• Chemical Name or Material: Ethoxyacetylene

Safety and Handling

Hazard Category	H225-H304-H312+H332-H315-H319-H336-H351-H361f-H373
Hazard Statement	GHS H Statement H225-H304-H361-H373-H315 Highly flammable liquid and vapour. May be fatal if swallowed and enters airways. Suspected of damaging fertility or the unborn child. May cause damage to organs through prolonged or repeated exposure. Causes skin irritation.
Precautionary Statement	P201-P202-P210-P233-P235-P240-P241-P242-P243-P260-P264b-P271-P280i-P281-P301+P310-P303+P361+P353-P304+P340-P305+P351+P338-P308+P313-P312-P331-P332+P313-P363-P370+P378q-P501c
DOTInformation	Transport Hazard Class: 3; Packing Group: II; Proper Shipping Name: FLAMMABLE LIQUIDS, N.O.S.
EINECSNumber	213-164-5
RTECSNumber	KN9900000
TSCA	No
Recommended Storage	Keep cold

SDS

RUO – Research Use Only