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MilliporeSigma™ Upstate™ Acetyl Histone H3 (Lys23), Rabbbit Polyclonal, ChIP Validated Antibody and Primer Set

Rabbit Polyclonal Antibody

Supplier:  MilliporeSigma™ 1710112

Catalog No. 17-101-12MI


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Description

Description

Specifically detects Acetyl Histone H3 (Lys23) Clone: in Human, S. cerevisiae, Vertebrate, Yeast samples, and it is validated for ChIP, Immunoprecipitation, Western Blotting

Histone H3 is one of the five main histone proteins involved in the structure of chromatin in eukaryotic cells. Featuring a main globular domain and a long N-terminal tail, H3 is involved with the structure of the nucleosomes of the 'beads on a string' structure. The N-terminal tail of histone H3 protrudes from the globular nucleosome core and can undergo several different types of epigenetic modifications that influence cellular processes. These modifications include the covalent attachment of methyl or acetyl groups to lysine and arginine amino acids and the phosphorylation of serine or threonine.
Specifications

Specifications

Acetyl Histone H3 (Lys23)
Polyclonal
Anti-Acetyl Histone H3 (Lys23) (rabbit polyclonal). One vial of 50μL of rabbit serum containing 0.05% sodium azide and 30% glycerol. Normal Rabbit Serum. One vial of 100μL of antiserum containing 0.05% sodium azide. Control Primers, human GAPDH promoter. One vial containing 75μL of 5μM each of primer specific for human GAPDH promoter. FOR: TAC TAG CGG TTT TAC GGG CG; REV: TCG AAC AGG AGG AGC AGA GAG CGA
HIST3H3, H3FT, MGC126886, H3t, MGC126888, H3T, H3/g, H3.4, H3/t
Ovalbumin-conjugated, synthetic peptide (KQLASAcKAARK-C) corresponding to amino acids 18-27 of yeast histone H3 acetylated on lysine 23 with a C-terminal cysteine added for conjugation purposes
RUO
Primary
Histone H3 acetylated on lysine 23. Does not recognize unacetylated recombinant histone H3
Human, S. cerevisiae, Vertebrates, Yeast
Serum
ChIP assay, Immunoprecipitation, Western Blot
Unconjugated
Q16695
Rabbit
25 Assays
Epigenetics and Nuclear Function
NM_003493
This ChIPAb+ Acetyl Histone H3 (Lys23) -ChIP Validated Antibody and Primer Set conveniently includes the antibody and the specific control PCR primers.
-20°C for up to 12 months from date of receipt; Upon first thaw and prior to removing the cap centrifuge the vial and gently mix the solution; Aliquot into microcentrifuge tubes and store at −20°C; Avoid repeated freeze/thaw cycles
SDS
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