Edvotek™ Sickle Cell Gene Detection
Gain an understanding of the effect of mutations on health and disease.
Supplier: Edvotek™ 116
- Genetically inherited diseases in humans can be caused by a single nucleotide mutation resulting in a change. Such a substitution can affect the structure and function of a critical protein, rendering it partially or completely nonfunctional. A classic example is hemoglobin in sickle cell anemia
- Agarose gel-based experiment designed for DNA staining and visualization with InstaStain™ Methylene Blue
- Demonstrates the use of a restriction enzyme that discriminates between the normal and sickle cell hemoglobin genes
- This experiment does not contain human DNA
|Sickle Cell Gene Detection (DNA-Based) Classroom Kit|
|Instructions; ready-to-load™ quickstrip™ dna samples; ultraspec agarose™ powder; practice gel loading solution; electrophoresis buffer; instastain™ blue and flashblue™|
|Electrophoresis apparatus, power supply, automatic micropipet and tips, balance, microwave or hot plate, visualization system|
|To investigate the restriction enzyme that discriminates between hba (normal) and hbs (disease) genes and perform a simulated test on a patient|
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