DL-Aminoglutethimide, 99%, Thermo Scientific Chemicals

Description

Aminoglutethimide is used to decrease the production of sex hormones and suppress the growth of tumors that need sex hormones to grow. It blocks the production of steroids derived from cholesterol and is clinically used in the treatment of Cushing's syndrome and metastatic breast cancer. It is also a drug of abuse by body builders.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Solubility
Soluble in water (2 mg/ml at 20°C), methanol (50 mg/ml), ethanol (7 mg/ml at 25°C), DMSO (20 mg/ml at 25°C), and chloroform.

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Keep away from strong oxidizing agents.

Specifications

Chemical Identifiers

• CAS: 125-84-8
• Molecular Formula: C13H16N2O2
• Molecular Weight (g/mol): 232.283
• MDL Number: MFCD00010122
• InChI Key: ROBVIMPUHSLWNV-UHFFFAOYSA-N
• Synonym: aminoglutethimide, dl-aminoglutethimide, cytadren, orimeten, p-aminoglutethimide, elipten, 3-4-aminophenyl-3-ethylpiperidine-2,6-dione, aminoglutetimida, 3-4-aminophenyl-3-ethyl-2,6-piperidinedione, aminoglutethimidum
• PubChem CID: 2145
• ChEBI: CHEBI:2654
• IUPAC Name: 3-(4-aminophenyl)-3-ethylpiperidine-2,6-dione
• SMILES: CCC1(CCC(=O)NC1=O)C2=CC=C(C=C2)N

• Melting Point: 152°C to 154°C
• Color: White
• Quantity: 25 g
• Merck Index: 14,440
• Solubility Information: Soluble in water (2mg/ml at 20°C),methanol (50mg/ml),ethanol (7mg/ml at 25°C),DMSO (20mg/ml at 25°C),and chloroform.
• Formula Weight: 232.28
• Percent Purity: 99%
• Physical Form: Powder
• Chemical Name or Material: DL-Aminoglutethimide

Safety and Handling

Hazard Category	H315-H319-H335
Hazard Statement	GHS H Statement H315-H319-H335 Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statement	P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P362-P501c
EINECSNumber	204-756-4
RTECSNumber	MA4026950
TSCA	No
Recommended Storage	Keep cold

SDS

RUO – Research Use Only