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  6. Dihydro-β-erythroidine hydrobromide, Tocris Bioscience™

Dihydro-β-erythroidine hydrobromide, Tocris Bioscience™

Catalog Number 234950
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
29734-68-7
C16H22BrNO3
356.26
GFIGWAJEIMHJJB-LINSIKMZSA-N
dihydro-beta-erythroidine hydrobromide, unii-ns1u03gc05, 2s,13bs-2-methoxy-2,3,5,6,8,9,10,13-octahydro-1h,12h-benzo i pyrano 3,4-g indolizin-12-one hydrobromide, dh?e, dihydro-?-erythroidine hydrobromide, 3, a-1,6-didehydro-14,17-dihydro-3-methoxy-16 15h-oxaerythrinan-15-one hydrobromide, 3beta-1,6-didehydro-14,17-dihydro-3-methoxy-16 15h-oxaerythrinan-15-one hydrobromide
11957537
COC1CC=C2CCN3C2(C1)C4=C(CC3)COC(=O)C4.Br
This item is not returnable. View return policy
29734-68-7
C16H22BrNO3
356.26
GFIGWAJEIMHJJB-LINSIKMZSA-N
dihydro-beta-erythroidine hydrobromide, unii-ns1u03gc05, 2s,13bs-2-methoxy-2,3,5,6,8,9,10,13-octahydro-1h,12h-benzo i pyrano 3,4-g indolizin-12-one hydrobromide, dh?e, dihydro-?-erythroidine hydrobromide, 3, a-1,6-didehydro-14,17-dihydro-3-methoxy-16 15h-oxaerythrinan-15-one hydrobromide, 3beta-1,6-didehydro-14,17-dihydro-3-methoxy-16 15h-oxaerythrinan-15-one hydrobromide
11957537
COC1CC=C2CCN3C2(C1)C4=C(CC3)COC(=O)C4.Br

Description

α4β2, muscle type and Torpedo nAChR antagonist

Dihydro-β-erythroidine hydrobromide is a member of the Erythrina alkaloids, it is a competitive nicotinic acetylcholine receptor antagonist with moderate selectivity for the neuronal α4 receptor subunit (IC50 values are 0.19 and 0.37 μM for α4β4 and α4β2 receptors, respectively). Antagonizes behavioral effects of nicotine in vivo. Dihydro-β-erythroidine blocks excitation of striatal GABAergic neurons, which completely suppress polysynaptic inhibition between striatal cholinergic interneurons. Dihydro-β-erythroidine hydrobromide has antidepressive-like effects in mice (forced swim and mouse suspension). Orally bioavailable
Quantity 50 mg
Formula Weight 356.26
Percent Purity >98%
Chemical Name or Material Dihydro-β-erythroidine hydrobromide

Safety and Handling

Recommended Storage Desiccate at Room Temperature
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