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  6. Dexamethasone acetate, Thermo Scientific Chemicals

Dexamethasone acetate, Thermo Scientific Chemicals

Catalog Number AAJ6369106
Click to view available options
Quantity:
1 g
5 g
1177-87-3
C24H31FO6
434.50
MFCD00027407
AKUJBENLRBOFTD-RPRRAYFGSA-N
dexamethasone acetate, 11b,16a-9-fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione 21-acetate
40469526
2-[(1R,2R,3aS,3bS,9aS,9bR,10S,11aS)-9b-fluoro-1,10-dihydroxy-2,9a,11a-trimethyl-7-oxo-1H,2H,3H,3aH,3bH,4H,5H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-1-yl]-2-oxoethyl acetate
C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)COC(C)=O
1177-87-3
C24H31FO6
434.50
MFCD00027407
AKUJBENLRBOFTD-RPRRAYFGSA-N
dexamethasone acetate, 11b,16a-9-fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione 21-acetate
40469526
2-[(1R,2R,3aS,3bS,9aS,9bR,10S,11aS)-9b-fluoro-1,10-dihydroxy-2,9a,11a-trimethyl-7-oxo-1H,2H,3H,3aH,3bH,4H,5H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-1-yl]-2-oxoethyl acetate
C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)COC(C)=O

Description

Dexamethasone has many uses in the treatment of cancer. Dexamethasone relieves inflammation in various parts of the body. To treat or prevent allergic reactions. As treatment of certain kinds of autoimmune diseases, skin conditions, asthma and other lung conditions. As treatment for a variety of cancers, such as leukemia, lymphoma, and multiple myeloma. It is also used for replacement therapy in adrenal insufficiency and in a screening test for the diagnosis of cushing's syndrome. Dexamethasone Acetate has also been determined to markedly decrease the number of activated macrophages. In addition, Dexamethasone Acetate has been observed to significantly decrease mRNA levels of TPH2 (tryptophan hydroxylase-2) in the raphe nuclei of C57/Bl6 mice.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Solubility
Soluble at 100 mg/ml in acetone

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents, heat.
TRUSTED_SUSTAINABILITY
Melting Point 240°C
Color White
Quantity 5 g
Beilstein 2342608
Merck Index 142943
Solubility Information Soluble at 100 mg/ml in acetone
Formula Weight 434.5
Physical Form Powder
Chemical Name or Material Dexamethasone acetate

Safety and Handling

Hazard Category Reproductive toxicity (category 2), Skin sensitisation (category 1), Specific target organ toxicity after repeated exposure (category 2)
Hazard Statement Suspected of damaging the unborn child, May cause an allergic skin reaction, May cause damage to organs through prolonged or repeated exposure
EINECSNumber 214-646-8
RTECSNumber TU4050000
TSCA Yes
Recommended Storage Keep cold
SDS

RUO – Research Use Only

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