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CP 154526, Tocris Bioscience™
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Quantity:
10 mg
50 mg
Description
Selective, non-peptide CRF1 receptor antagonist (Ki values are 2.7 and > 10000 nM for CRF1 and CRF2 receptors respectively). Blocks CRF-induced adenylate cyclase activation (Ki = 3.7 nM) and attenuates activation of the HPA axis by CRF. Displays anxiolytic-like activity in the rat elevated plus-maze test; brain penetrant.
Specifications
Quantity | 50 mg |
Formula Weight | 400.99 |
Percent Purity | >99% |
Chemical Name or Material | CP 154526 |
Safety and Handling
Recommended Storage | Desiccate at +4°C |
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