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CP 100356 hydrochloride, Tocris Bioscience™
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Quantity:
10 mg
50 mg
Description
High affinity P-glycoprotein (P-gp) inhibitor (Ki values are 58 and 94 nM for mouse Pgp1a and Pgp1b isoforms). Inhibits calcein-AM uptake in MDR1-transfected MDCKII cells (IC50 = 0.5 μM) and prazosin transport in BCRP-transfected MDCKII cells (IC50 = 1.5 μM). Displays weak or no inhibitory activity against MRP1, OATP1B1 and several major human P450 enzymes (IC50 > 50 μM).
Specifications
Quantity | 50 mg |
Formula Weight | 597.1 |
Percent Purity | >98% |
Chemical Name or Material | CP 100356 hydrochloride |
Safety and Handling
Recommended Storage | Desiccate at Room Temperature |
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