Carbadox, 98+%, Thermo Scientific Chemicals

Description

Carbadox has been used to suppress aldosterone production, to study the spread of shiga toxin-producing Escherichia coli (STEC) strains, and to compare different antimicrobial activities. Carbadox is a quinoxaline-di-N-oxide antibiotic that is generally used in feed to swine to prevent dysentery and improve feed efficiency. It inhibits bacteria by intercalation and induction of mutations in bacterial genome.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Carbadox has been used to suppress aldosterone production, to study the spread of shiga toxin-producing Escherichia coli (STEC) strains, and to compare different antimicrobial activities. Carbadox is a quinoxaline-di-N-oxide antibiotic that is generally used in feed to swine to prevent dysentery and improve feed efficiency. It inhibits bacteria by intercalation and induction of mutations in bacterial genome.

Solubility
Soluble in 1N NaOH (50 mg/ml), and water (partly).

Notes
Store in cool, dry place in a tightly sealed container. Store away from oxidizing agents.

Specifications

• Melting Point: 239°C to 240°C
• Color: Yellow
• Flash Point: 18°C (64°F)
• Molecular Formula: C11H10N4O4
• Quantity: 100 g
• UN Number: UN1325
• Merck Index: 14,1780
• Synonym: carbadox, unii-m2x04r2e2y, getroxel, mecadox, dsstox_cid_23913, dsstox_rid_80088, dsstox_gsid_43913, fortigro, karbadox czech, methyl n-e-1-hydroxy-4-oxidoquinoxalin-4-ium-2-ylidene methyl iminocarbamate
• Solubility Information: Soluble in 1N NaOH (50mg/ml),and water (partly).
• InChI Key: BPMVRAQIQQEBLN-UHFFFAOYSA-N
• SMILES: COC(=O)N=NC=C1C=[N+](C2=CC=CC=C2N1O)[O-]
• IUPAC Name: methyl N-[(E)-(1-hydroxy-4-oxidoquinoxalin-4-ium-2-ylidene)methyl]iminocarbamate
• Molecular Weight (g/mol): 262.23
• PubChem CID: 5353472
• Formula Weight: 262.22
• Percent Purity: ≥98%
• Physical Form: Solid
• Chemical Name or Material: Carbadox

Safety and Handling

Hazard Category	H228-H302-H350
Hazard Statement	GHS H Statement H228-H350-H302 Flammable solid. May cause cancer. Harmful if swallowed.
Precautionary Statement	P201-P202-P210-P240-P241-P264b-P270-P281-P301+P312-P308+P313-P330-P370+P378q-P501c
DOTInformation	Transport Hazard Class: 4.1; Packing Group: II; Proper Shipping Name: FLAMMABLE SOLIDS, ORGANIC, N.O.S.
RTECSNumber	FE2779000
TSCA	No
Recommended Storage	Ambient temperatures

SDS

RUO – Research Use Only