C1q Monoclonal Antibody (JL-1), Biotin, Invitrogen™

Mouse Monoclonal Antibody

Supplier:  Thermo Scientific MA140312

Catalog No. MA140312

Description

MA1-40312 detects C1q from mouse samples. MA1-40312 has been successfully used in immunohistochemistry (frozen), ELISA, immunofluorescence, functional assays and Western blot applications. The MA1-40312 immunogen is purified mouse C1q. Positive control: Spleen and kidney tissue of wild-type mice ; Negative control: Spleen and kidney tissue of C1q -/- mice.

C1q is a sub-component of complement C1. C1q associates with complement components C1r and C1s, which are required for the progression of the proteolytic complement cascade. Deficiency of C1q has been associated with lupus erythematosus and glomerulonephritis. C1q is composed of 18 polypeptide chains: six A-chains, six B-chains, and six C-chains. Each chain contains a collagen-like region located near the N terminus and a C-terminal globular region. The A-, B-, and C-chains are arranged in the order A-C-B on chromosome 1.

Specifications

• Antigen: C1q
• Classification: Monoclonal
• Concentration: 0.1 mg/mL
• Formulation: PBS with 0.1% BSA and 0.02% sodium azide
• Gene Accession No.: P02745, P02746, P02747, P14106, P31720, P31721, P31722, P98086, Q02105
• Gene Symbols: C1QA, C1QB, C1qc
• Immunogen: Purified mouse C1q
• Quantity: 50 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG2b

• Applications: ELISA, Functional Assay, Immunohistochemistry (Frozen), Western Blot
• Clone: JL-1
• Conjugate: Biotin
• Gene: C1QB
• Gene Alias: AI255395; AI385742; C1q; C1qa; C1qb; C1qc; C1Q-C; C1QG; Ciqc; complement C1q A chain; complement C1q B chain; complement C1q C chain; complement C1q chain A; complement C1q chain B; complement C1q subcomponent subunit A; complement C1q subcomponent subunit A-like protein; Complement C1q subcomponent subunit B; Complement C1q subcomponent subunit C; complement component 1, q subcomponent, A chain; complement component 1, q subcomponent, alpha polypeptide; complement component 1, q subcomponent, B chain; complement component 1, q subcomponent, beta polypeptide; complement component 1, q subcomponent, C chain; complement component 1, q subcomponent, c polypeptide; complement component 1, q subcomponent, gamma polypeptide; complement component C1q, A chain; complement component C1q, B chain; complement subcomponent C1q chain B
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 12259, 12260, 12262, 29687, 298566, 362634, 712, 713, 714
• Content And Storage: 4° C
• Form: Liquid