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BIO, Tocris Bioscience™
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Quantity:
10 mg
50 mg
Description
Potent ATP-competitive glycogen synthase kinase-3 (GSK-3) inhibitor (IC50 = 5 nM). Also inhibits cyclin-dependent kinases (cdks; IC50 values are <100 nM for cdk2 and 5 and sub micromolar for cdk1, cdk4 and cdk9). Maintains self-renewal and pluripotency in embryonic stem cells via activation of the Wnt signaling pathway in vitro; also promotes proliferation and dedifferentiation in cardiomyocytes.
Negative Control also available.
Specifications
Quantity | 50 mg |
Formula Weight | 356.17 |
Percent Purity | >98% |
Chemical Name or Material | BIO |
Safety and Handling
Recommended Storage | Store at +4°C |
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