Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
Learn More
BD Pharmingen™ IHC Zinc Fixative
An alternative to formalin fixation of tissue for paraffin embedded sections
$86.40 - $225.00
Specifications
| Color | Clear |
|---|---|
| Content And Storage | Room temperature |
| Product Type | Fixative |
| For Use With (Application) | Immunohistochemical staining |
| Form | Liquid |
Description
Ten percent neutral buffered formalin fixes tissue by cross-linking proteins, potentially causing a conformational change or “masking” of the antigenic epitope and leading to reduced or absent antibody reactivity. Different antigen retrieval techniques are used to unmask the epitope; however, many times it is not possible to retrieve the epitope and get optimal immunohistochemical staining. In these situations the use of IHC Zinc fixative, which is a milder fixative than formalin, is recommended.
- Zinc-fixed paraffin embedded sections show very good immunostaining with many leukocytes markers and depict tissue morphology comparable to formalin-fixation
- Use of antigen retrieval techniques on the zinc-fixed paraffin sections may further enhance the antibody reactivity in some cases
There are a few antigens that are not preserved by zinc-fixation. In these situations use of fresh frozen tissue for immunohistochemical staining is the only alternative.
Specifications
| Clear | |
| Fixative | |
| Liquid |
| Room temperature | |
| Immunohistochemical staining |
Spot an opportunity for improvement?
Product Content Correction
Product Content Correction
Your input is important to us. Please complete this form to provide feedback related to the content on this product.
Product Title