BD Biotin Annexin V

For flow cytometric analysis of cells that are undergoing apoptosis

Catalog Number	Mfr. No.	Quantity
BDB556418	BD 556418	100 Tests
BDB556417	BD 556417	200 Tests

Description

Apoptosis is a normal physiologic process which occurs during embryonic development as well as in maintenence of tissue homeostasis. The apoptotic program is characterized by certain morphologic features, including loss of plasma membrane asymmetry and attachment, condensation of cytoplasm and nucleus, and internucleosomal cleavage of DNA. In apoptotic cells, the membrane phospholipid phosphatidylserine (PS) is translocated from inner to outer leaflet of plasma membrane, thereby exposing PS to external cellular environment

• 35-36 kDa Ca2+ dependent phospholipid-binding protein that has high affinity for PS
• Binds to cells with exposed PS
• May be conjugated to fluorochromes, such as fluorescein isothiocyanate (FITC), to serve as sensitive probe
• Typically used in conjunction with vital dye such as 7-Amino-Actinomycin
• Storage Buffer: Aqueous buffered solution containing ≤0.09% sodium azide
• Format: Purified

Flow cytometry, Blocking

Specifications

• For Use With (Application): Flow Cytometry
• Molecular Weight (g/mol): 35 to 36
• Storage Requirements: -80°C
• Form: Liquid

• Formulation: Aqueous Buffered solution containing ≤0.09% Sodium Azide
• Name: Biotin Annexin V
• Recombinant: Recombinant

Research use only