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BAY 41-8543, >98%, Tocris Bioscience™
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Quantity:
10 mg
50 mg
Description
Guanylyl cyclase (sGC) stimulator. Increases activity of sGC by up to 92-fold at concentrations up to 100 μM. Induces relaxation of aorta, saphenous arteries, coronary arteries and veins in vitro. Inhibits collagen-induced platelet aggregation. Promotes lipid uptake into brown adipose tissue and increases energy expenditure in mice. Induces weight loss in obese mice. Antihypertensive.
Specifications
Linear Formula | C21H21FN8O |
Quantity | 50 mg |
Solubility Information | Soluble to 10mM in DMSO with gentle warming |
Formula Weight | 420.44 |
Percent Purity | >98% |
Chemical Name or Material | 2-[1-[(2-Fluorophenyl)methyl]-1H-pyrazolo[3,4-b]pyridin-3-yl]-5-(4-morpholinyl)-4,6-pyrimidinediamin |
Grade | >98% |
Safety and Handling
Recommended Storage | Store at −20°C |
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