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Bay 11-7821, Tocris Bioscience™

Catalog Number 174410
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Quantity:
10 mg
This item is not returnable. View return policy
19542-67-7
C10H9NO2S
207.25
MFCD00712162
DOEWDSDBFRHVAP-KRXBUXKQSA-N
e-3-tosylacrylonitrile, e-3-p-toluenesulfonyl acrylonitrile, unii-4y5g2a4f6o, e-3-4-methylphenyl sulfonylprop-2-enenitrile, 3-p-toluenesulfonyl acrylonitrile, e, 3-4-methylphenylsulfonyl-2-propenenitrile, e-3-4-methylphenylsulfonyl-2-propenenitrile, e 3-4-methylphenyl sulfonyl-2-propenenitrile, 2e-3-4-methylphenyl sulfonyl prop-2-enenitrile, 2-propenenitrile, 3-4-methylphenyl sulfonyl-, 2e
5353431
CHEBI:85928
(2E)-3-(4-methylbenzenesulfonyl)prop-2-enenitrile
CC1=CC=C(C=C1)S(=O)(=O)\C=C\C#N
This item is not returnable. View return policy
19542-67-7
C10H9NO2S
207.25
MFCD00712162
DOEWDSDBFRHVAP-KRXBUXKQSA-N
e-3-tosylacrylonitrile, e-3-p-toluenesulfonyl acrylonitrile, unii-4y5g2a4f6o, e-3-4-methylphenyl sulfonylprop-2-enenitrile, 3-p-toluenesulfonyl acrylonitrile, e, 3-4-methylphenylsulfonyl-2-propenenitrile, e-3-4-methylphenylsulfonyl-2-propenenitrile, e 3-4-methylphenyl sulfonyl-2-propenenitrile, 2e-3-4-methylphenyl sulfonyl prop-2-enenitrile, 2-propenenitrile, 3-4-methylphenyl sulfonyl-, 2e
5353431
CHEBI:85928
(2E)-3-(4-methylbenzenesulfonyl)prop-2-enenitrile
CC1=CC=C(C=C1)S(=O)(=O)\C=C\C#N

Description

E2 ubiquitin (Ub) conjugating enzymes inhibitor

E2 ubiquitin (Ub) conjugating enzyme inhibitor. Inhibits the conjugation of Ub to a range of E2 enzymes. Inhibits E2 enzyme mediated IκBα phosphorylation and indirectly decreases NF-κb activity. Also reversibly activates MAPK signaling. Induces apoptosis of leukemic T cell and B-cell lymphoma cell lines. Also inhibits activation of NLRP3 inflammasome.
Quantity 10 mg
Formula Weight 207.25
Percent Purity >99%
Chemical Name or Material Bay 11-7821

Safety and Handling

Recommended Storage Store at +4°C
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