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Tocris Bioscience™ Azidothymidine
Selective reverse transcriptase inhibitor; antiretroviral
Supplier: Tocris Bioscience™ 4150/50
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Description
Selective reverse transcriptase inhibitor. Exhibits 100-fold selectivity for HIV reverse transcriptase over DNA polymerase α. Suppresses HIV-1 replication and enhances cell viability in HIV-1 infected T cells. Attenuates growth of multiple myeloma (MM) cells in vitro and reduces growth of MM tumor xenografts in mice. Increases differentiation iPSCs into cortical neurons and reduces the over-proliferation of neural precursors. Orally bioavailable and brain penetrant. Antiretroviral agent. Also decreases CRISPR-mediated homology directed repair (HDR) efficiency.Specifications
| 99% | |
| 30516-87-1 | |
| 50 mg | |
| M.W. (Observed): 267.24 |
| 3 '-Azido-3 '-deoxythymidine | |
| -20°C | |
| Azidothymidine | |
| Azidothymidine |
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