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  7. AZD 6482, Tocris Bioscience™

AZD 6482, Tocris Bioscience™

Catalog Number 483950
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
1173900-33-8
C22H24N4O4
408.458
IRTDIKMSKMREGO-OAHLLOKOSA-N
r-2-1-7-methyl-2-morpholino-4-oxo-4h-pyrido 1,2-a pyrimidin-9-yl ethylamino benzoic acid, 2-1r-1-7-methyl-2-4-morpholinyl-4-oxo-4h-pyrido 1,2-a pyrimidin-9-yl ethyl amino benzoic acid, unii-78g6mp5pz5, 2-1r-1-7-methyl-2-morpholin-4-yl-4-oxopyrido 1,2-a pyrimidin-9-yl ethyl amino benzoic acid, 4urk, pubchem19330, d0d0qa, azd 6482 who-dd
44137675
2-[[(1R)-1-(7-methyl-2-morpholin-4-yl-4-oxopyrido[1,2-a]pyrimidin-9-yl)ethyl]amino]benzoic acid
CC1=CN2C(=O)C=C(N=C2C(=C1)C(C)NC3=CC=CC=C3C(=O)O)N4CCOCC4
This item is not returnable. View return policy
1173900-33-8
C22H24N4O4
408.458
IRTDIKMSKMREGO-OAHLLOKOSA-N
r-2-1-7-methyl-2-morpholino-4-oxo-4h-pyrido 1,2-a pyrimidin-9-yl ethylamino benzoic acid, 2-1r-1-7-methyl-2-4-morpholinyl-4-oxo-4h-pyrido 1,2-a pyrimidin-9-yl ethyl amino benzoic acid, unii-78g6mp5pz5, 2-1r-1-7-methyl-2-morpholin-4-yl-4-oxopyrido 1,2-a pyrimidin-9-yl ethyl amino benzoic acid, 4urk, pubchem19330, d0d0qa, azd 6482 who-dd
44137675
2-[[(1R)-1-(7-methyl-2-morpholin-4-yl-4-oxopyrido[1,2-a]pyrimidin-9-yl)ethyl]amino]benzoic acid
CC1=CN2C(=O)C=C(N=C2C(=C1)C(C)NC3=CC=CC=C3C(=O)O)N4CCOCC4

Description

Potent and selective PI 3-Kβ inhibitor

Potent and selective inhibitor of PI 3-kinase β (PI 3-Kβ) (IC50 values are 0.69, 13.6, 47.8 and 136 nM for PI 3-Kβ, PI 3-Kδ, PI 3-Kγ and PI 3-Kα, respectively). Selectively inhibits in vivo growth of the PTEN-deficient tumor xenografts HCC70 and PC3. Also exhibits antithrombotic activity.
Quantity 50 mg
Formula Weight 408.45
Percent Purity >98%
Chemical Name or Material AZD 6482

Safety and Handling

Recommended Storage Store at -20°C
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