TRA-1-81 Mouse anti-Human, FITC, Clone: TRA-1-81, BD

Mouse Monoclonal Antibody

Supplier:  BD Biosciences 560194

Catalog No. BDB560194

Description

The TRA-1-81 monoclonal antibody reacts with a pluripotent-stem-cell-specific epitope on a high-molecular-weight transmembrane glycoprotein. The TRA-1-81 antigen is an epitope on the same keratan sulfate core molecule, podocalyxin, as 4 other distinct antigens on tumor-derived cell lines, TRA-1-60, GCTM2, K4, and K21. The expression of TRA-1-81 antigen is stage-specific and can be used to characterize embryonic cells and monitor their differentiation. The antigen is found on teratocarcinoma (embryonal carcinoma or EC), embryonic inner cell mass (but not morula or trophoblast), and embryonic stem (ES) cells. As human EC and ES cells undergo differentiation, expression of TRA-1-81 antigen is lost.

Host Species: Mouse
Clone: TRA-1-81
Isotype: IgM, κ
Species Reactivity: Human
Immunogen: Human Embryonal Carcinoma Cell Line

Flow Cytometry

Specifications

• Antigen: TRA-1-81
• Classification: Monoclonal
• Conjugate: FITC
• Host Species: Mouse
• Purification Method: Affinity Purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

• Applications: Flow Cytometry
• Clone: TRA-1-81
• Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
• Immunogen: Human Embryonal Carcinoma Cell Line
• Quantity: 100 Tests
• Research Discipline: Cell Biology
• Target Species: Human
• Isotype: IgM κ