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Advanced ImmunoChemical, Inc. Monoclonal Mouse Anti-Human Proinsulin, 0.2mg
SDP

Supplier:  Advanced ImmunoChemical, Inc. 1PINS0.2MG

Encompass_Preferred

This item is manufactured by HyTest, Ltd and distributed by Advanced ImmunoChemical, Inc.

Monoclonal antibodies / Metabolic Syndrome / Monoclonal mouse anti-human proinsulin. MAbs: 3A1, 1G4, 1D6; Hybridoma clones have been derived from hybridization of X63-Ag8-653 myeloma cells with spleen cells of Balb/c mice immunized with purified human proinsulin

Specificity: MAbs 3A1 and 1G4 are directed to different antigenic determinants. MAb 3A1 reacts with the site of connection of C-peptide and C-end of B-chain of proinsulin molecule. MAbs 1D6 reacts with different epitopes on human proinsulin molecule; both of each are generated by the interactions between insulin and C-peptide parts of prohormone. Kd for MAb 3A1 is 1.1 x 10-8 M.Kd for MAb 1G4 is 2.6 x 10-7 M. Kd for MAb 1D6 is >3 x 10-8 M. MAbs 3A1, 1G4, 1D6 do not cross-react with human, bovine and porcine insulin, bovine and porcine proinsulin, and human C-peptide.

Catalog No. 50-153-9845


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