CD16/CD32 Rat anti-Mouse, Unlabeled, Clone: 2.4G2, BD

Rat Monoclonal Antibody

Supplier:  BD Biosciences 553141

Catalog No. BDB553141

Description

The 2.4G2 antibody reacts specifically with a common nonpolymorphic epitope on the extracellular domains of the mouse Fc γ III and Fc γ II receptors. It has also been reported to bind the Fc γ I receptor (CD64) via its Fc domain. 2.4G2 mAb blocks non-antigen-specific binding of immunoglobulins to the Fc γ III and Fc γ II, and possibly Fc γ I, receptors in vitro and in vivo . CD16 and/or CD32 are expressed on natural killer cells, monocytes, macrophages, dendritic cells (at low levels), Kupffer cells, granulocytes, mast cells, B lymphocytes, immature thymocytes, and some activated mature T lymphocytes.

Specifications

• Antigen: CD16/CD32
• Classification: Monoclonal
• Concentration: 0.5mg/mL
• Description: FcγRIII/FcγRII; Fcgr3/Fcgr2
• Host Species: Rat
• Purification Method: Affinity Purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Content And Storage: Store undiluted at 4°C

• Applications: Blocking Assay, Flow Cytometry
• Clone: 2.4G2
• Conjugate: Unconjugated
• Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
• Immunogen: Mouse BALB/c Macrophage J774 Cell Line
• Quantity: 0.1 mg
• Research Discipline: Immunology
• Target Species: Mouse
• Isotype: IgG2b κ

For Research Use Only.