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  6. Ampicillin sodium salt, Thermo Scientific Chemicals

Ampicillin sodium salt, Thermo Scientific Chemicals

Catalog Number AAJ6380709
Click to view available options
Quantity:
5 g
10 g
69-52-3
C16H21N3NaO4S
374.411
MFCD00064313
BSFVNXCYXDYHOD-ZQDFAFASSA-N
131673879
(2S,5R,6R)-6-[[(2R)-2-amino-2-phenylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid;molecular hydrogen;sodium
[HH].CC1(C(N2C(S1)C(C2=O)NC(=O)C(C3=CC=CC=C3)N)C(=O)O)C.[Na]
69-52-3
C16H21N3NaO4S
374.411
MFCD00064313
BSFVNXCYXDYHOD-ZQDFAFASSA-N
131673879
(2S,5R,6R)-6-[[(2R)-2-amino-2-phenylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid;molecular hydrogen;sodium
[HH].CC1(C(N2C(S1)C(C2=O)NC(=O)C(C3=CC=CC=C3)N)C(=O)O)C.[Na]

Description

Ampicillin sodium salt, CAS # 69-52-3, is the sodium salt form of ampicillin, a semisynthetic derivative of aminopenicillin compound that shows antibacterial activity against both gram-positive and gram-negative bacteria.

Ampicillin sodium salt is a reagent for transformed cells expressing beta-lactamase. It acts as a structural analogue of acyl-D-alanyl-D-alanine, acylates the transpeptidase enzyme and prevents the cross-linking of the peptidoglycan of the cell wall necessary for the growth of the bacterium.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

• Ampicillin sodium salt is a semi-synthetic derivative of penicillin with a broad-spectrum antibacterial activity against several species, including Bacillus subtilis, Staphylococcus aureus, Escherichia coli, and Ralstonia solanacearum

• It can inhibit bacterial cell wall synthesis by binding to penicillin-binding proteins, inhibiting peptidoglycan synthesis, which is an essential component of the bacterial cell wall

Application

• Ampicillin sodium salt has been used as a reagent for transformed cells that express β-lactamase

• It can be used to select for ampicillin resistance in mutated and transformed cells

• Ampicillin sodium salt acts as a structural analog of acyl-D-alanyl-D-alanine, acylates the transpeptidase enzyme preventing the cross-linking of the cell wall peptidoglycan, which is necessary for the growth of the bacterium

TRUSTED_SUSTAINABILITY
Type Ampicillin Sodium Salt
Physical Form Powder
Melting Point 215°C
Beilstein 4119211
Merck Index 14,586
Solubility Information Freely soluble in water; Sparingly soluble in acetone
Formula Weight 371.39
Color White
Quantity 10 g
Chemical Name or Material Ampicillin sodium salt

Safety and Handling

Hazard Category H317-H334
Hazard Statement GHS H Statement
H334-H317
May cause allergy or asthma symptoms or breathing difficulties if inhaled.
May cause an allergic skin reaction.
Precautionary Statement P260-P271-P272-P280g-P285-P302+P352-P304+P340-P314-P333+P313-P342+P311-P363-P501c
EINECSNumber 200-708-1
RTECSNumber XH8400000
TSCA No
Recommended Storage Keep cold
SDS

RUO – Research Use Only

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