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Amlodipine besylate, 98+%, Thermo Scientific Chemicals
Description
Amlodipine besylate is used as a dihydropyridine calcium channel blocker. It is also used as an antianginal and antihypertensive. Amlodipine besylate also displays vasoprotective effects in cardiovascular disease and inhibits Ca2+-induced contractions in depolarized rat aorta (IC50 = 1.9 nM). Amlodipine besylate has been shown to inhibit proliferation of human vascular smooth muscle cells and epidermoid carcinoma A431 cells.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Amlodipine besylate is used as a dihydropyridine calcium channel blocker. It is also used as an antianginal and antihypertensive. Amlodipine besylate also displays vasoprotective effects in cardiovascular disease and inhibits Ca2+-induced contractions in depolarized rat aorta (IC50 = 1.9 nM). Amlodipine besylate has been shown to inhibit proliferation of human vascular smooth muscle cells and epidermoid carcinoma A431 cells.
Solubility
Soluble in DMSO (≥20 mg/mL), water (10 mM), chloroform, ethanol (≥14 mg/mL), and methanol.
Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Keep away from strong oxidizing agents.
Specifications
Specifications
Melting Point | 195°C to 204°C |
Color | White |
Quantity | 1 g |
Merck Index | 14,491 |
Solubility Information | Soluble in DMSO (?20mg/mL),water (10 mM),chloroform,ethanol (?14mg/mL),and methanol. |
Formula Weight | 567.05 |
Percent Purity | ≥98% |
Physical Form | Solid |
Chemical Name or Material | Amlodipine besylate |
Safety and Handling
Hazard Category | H302-H315-H319-H335 |
Hazard Statement | GHS H Statement H302-H315-H319-H335 Harmful if swallowed. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation. |
Precautionary Statement | P261-P264b-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P312-P330-P332+P313-P362-P501c |
RTECSNumber | US7967700 |
TSCA | No |
Recommended Storage | Ambient temperatures |
RUO – Research Use Only
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