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Aluminon, Thermo Scientific Chemicals

Catalog Number AAA1540109
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Quantity:
10 g
50 g
250 g
569-58-4
C22H23N3O9
473.438
MFCD00040925
AIPNSHNRCQOTRI-UHFFFAOYSA-N
Aurintricarboxylic acid triammonium salt
54729869
CHEBI:87398
triazanium;5-[(3-carboxy-4-oxidophenyl)-(3-carboxy-4-oxocyclohexa-2,5-dien-1-ylidene)methyl]-2-oxidobenzoate
C1=CC(=C(C=C1C(=C2C=CC(=O)C(=C2)C(=O)O)C3=CC(=C(C=C3)[O-])C(=O)[O-])C(=O)O)[O-].[NH4+].[NH4+].[NH4+]
569-58-4
C22H23N3O9
473.438
MFCD00040925
AIPNSHNRCQOTRI-UHFFFAOYSA-N
Aurintricarboxylic acid triammonium salt
54729869
CHEBI:87398
triazanium;5-[(3-carboxy-4-oxidophenyl)-(3-carboxy-4-oxocyclohexa-2,5-dien-1-ylidene)methyl]-2-oxidobenzoate
C1=CC(=C(C=C1C(=C2C=CC(=O)C(=C2)C(=O)O)C3=CC(=C(C=C3)[O-])C(=O)[O-])C(=O)O)[O-].[NH4+].[NH4+].[NH4+]

Description

It is a potent inhibitor of ribonuclease and topoisomerase II by preventing the binding of the nucleic acid to the enzyme. It stimulates tyrosine phosphorylation processes including the Jak2/STAT5 pathway in NB2 lymphoma cells, ErbB4 in neuroblastoma cells, and MAP kinases, Shc proteins, phosphatidylinositide 3-kinase and phospholipase C in PC12 cells. Aurintricarboxylic acid inhibits apoptosis in many cell types.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
It is a potent inhibitor of ribonuclease and topoisomerase II by preventing the binding of the nucleic acid to the enzyme. It stimulates tyrosine phosphorylation processes including the Jak2/STAT5 pathway in NB2 lymphoma cells, ErbB4 in neuroblastoma cells, and MAP kinases, Shc proteins, phosphatidylinositide 3-kinase and phospholipase C in PC12 cells. Aurintricarboxylic acid inhibits apoptosis in many cell types.

Solubility
Soluble in water(800g/L).

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents.
TRUSTED_SUSTAINABILITY
Melting Point 220°C to 225°C (decomposition)
Merck Index 14,322
Solubility Information Soluble in water(800g/L).
Formula Weight 473.44
Odor Odorless
pH 5.3
Quantity 10 g
Chemical Name or Material Aluminon

Safety and Handling

Hazard Category H315-H319
Hazard Statement GHS H Statement
H315-H319
Causes skin irritation.
Causes serious eye irritation.
Precautionary Statement P264b-P280-P302+P352-P305+P351+P338-P332+P313-P362
EINECSNumber 209-319-1
RTECSNumber GU4800000
TSCA Yes
Recommended Storage Ambient temperatures
SDS

RUO – Research Use Only

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