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  7. Acifran, Tocris Bioscience™

Acifran, Tocris Bioscience™

Catalog Number 176250
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
72420-38-3
C12H10O4
218.208
DFDGRKNOFOJBAJ-UHFFFAOYSA-N
acifran, reductol, acifran usan:inn, acifranum inn-latin, unii-fp3llw01bl, unii-61iz92gn57, fp3llw01bl, 2-furancarboxylic acid, 4,5-dihydro-5-methyl-4-oxo-5-phenyl, 4,5-dihydro-5-methyl-4-oxo-5-phenyl-2-furancarboxylic acid, +--4,5-dihydro-5-methyl-4-oxo-5-phenyl-2-furoic acid
51576
5-methyl-4-oxo-5-phenylfuran-2-carboxylic acid
CC1(C(=O)C=C(O1)C(=O)O)C2=CC=CC=C2
This item is not returnable. View return policy
72420-38-3
C12H10O4
218.208
DFDGRKNOFOJBAJ-UHFFFAOYSA-N
acifran, reductol, acifran usan:inn, acifranum inn-latin, unii-fp3llw01bl, unii-61iz92gn57, fp3llw01bl, 2-furancarboxylic acid, 4,5-dihydro-5-methyl-4-oxo-5-phenyl, 4,5-dihydro-5-methyl-4-oxo-5-phenyl-2-furancarboxylic acid, +--4,5-dihydro-5-methyl-4-oxo-5-phenyl-2-furoic acid
51576
5-methyl-4-oxo-5-phenylfuran-2-carboxylic acid
CC1(C(=O)C=C(O1)C(=O)O)C2=CC=CC=C2

Description

Hypolipidemic agent; agonist for the GPR109A (HM74A) and GPR109B receptors

Hypolipidemic agent. Exhibits higher potency than nicotinic acid and clofibrate. Full and potent agonist at the human orphan GPCR HM74A/GPR109A and GPR109B (EC50 values are 1.3 and 4.2 μM respectively). Reduces serum triglycerides and circulating LDL-cholesterol in vivo, without affecting liver weight or liver enzymes.
Quantity 50 mg
Formula Weight 218.21
Percent Purity >99%
Chemical Name or Material Acifran

Safety and Handling

Recommended Storage Store at +4°C
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