Acetylsalicylic acid, 99%, Thermo Scientific Chemicals

Description

Acetylsalicylic acid, aspirin, CAS# 50-78-2, is a non-steroidal anti-inflammatory that is used widely as an analgesic and antipyretic.

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General description
• Acetylsalicylic acid is a common non-steroidal anti-inflammatory (NSAID) and
• Acetylsalicylic acid works by inhibiting cyclooxygenases, reducing prostaglandin production and the release of pyrogens

Applications
• Acetylsalicylic acid is useful for research on fever, postoperative pain, blood clots, and inflammation
• Acetylsalicylic acid may also be used in the study of cancer prevention
• Intended for research use only

Literature references

Levine, G.N.; Bates, E.R.; Bittl, J.A.; Brindis, R.G.; Fihn, S.D.; Fleisher, L.A.; Granger, C.B.; Lange, R.A.; Mack, M.J.; Mauri, L.; Mehran, R.; Mukherjee, D.; Newby, L.K.; O'Gara, P.T.; Sabatine, M.S.; Smith, P.K.; Smith, S.C. Jr. 2016, ACC/AHA Guideline Focused Update on Duration of Dual Antiplatelet Therapy in Patients With Coronary Artery Disease: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines. J Am Coll Cardiol. 2016, 68(10), 1082-115.

Hoffman, M.K.; Goudar, S.S.; Kodkany, B.S.; Metgud, M.; Somannavar, M.; Okitawutshu, J.; Lokangaka, A.; Tshefu, A.; Bose, C.L.; Mwapule, A.; Mwenechanya, M.; Chomba, E.; Carlo, W.A.; Chicuy, J.; Figueroa, L.; Garces, A.; Krebs, N.F.; Jessani, S.; Zehra F.; Saleem, S.; Goldenberg, R.L.; Kurhe, K.; Das, P.; Patel, A.; Hibberd, P.L.; Achieng, E.; Nyongesa, P.; Esamai, F.; Liechty, E.A.; Goco, N.; Hemingway-Foday, J.; Moore, J.; Nolen, T.L.; McClure, E.M.; Koso-Thomas, M.; Miodovnik, M.; Silver, R.; Derman, R.J. ASPIRIN Study Group. Low-dose aspirin for the prevention of preterm delivery in nulliparous women with a singleton pregnancy (ASPIRIN): a randomised, double-blind, placebo-controlled trial. Lancet. 2020, 25, 395(10220), 285-293.

Specifications

• CAS Min %: 98.5
• CAS Max %: 100.0
• Melting Point: 136.0°C to 140.0°C
• Color: White
• Density: 1.3500g/mL
• Flash Point: 250°C
• Loss on Drying: 0.5% max. (1 g) (vacuum)
• Infrared Spectrum: Authentic
• Assay Percent Range: 99%
• Packaging: Plastic bottle
• Linear Formula: 2-(CH₃CO₂)C₆H₄CO₂H
• Quantity: 50 g
• Beilstein: 10, 67
• Specific Gravity: 1.35
• Merck Index: 15, 841
• Solubility Information: Solubility in water: 3.3g/L (20°C). Other solubilities: 1g in 5mL alcohol,17mL chloroform,,and 10-15 mL ether,slightly soluble in anhydrous ether,decomposes in boiling water,alkali
• Formula Weight: 180.16
• Percent Purity: 99%
• Physical Form: Granular Powder
• Chemical Name or Material: Acetylsalicylic acid

Safety and Handling

Hazard Category	GHS Signal Word: Warning
Hazard Statement	GHS H Statement Harmful if swallowed.
Precautionary Statement	GHS P Statement IF SWALLOWED: rinse mouth. Do NOT induce vomiting. Call a POISON CENTER or doctor/physician if you feel unwell. Wash face,hands and any exposed skin thoroughly after handling.
EINECSNumber	200-064-1

SDS

RUO – Research Use Only