Thermo Scientific™ Accucore™ PREP XL C8 HPLC Columns

Achieve purification of moderately hydrophobic analytes on this solid core column.

Catalog Number	Mfr. No.	Particle Size	Diameter (Metric)	Length (Metric)
03-254-022	Thermo Scientific™ 74204018823A	5 μm	10 mm	8 mm
03-254-023	Thermo Scientific™ 74204019023A	5 μm	10 mm	20 mm
03-254-016	Thermo Scientific™ 74204059070A	5 μm	10 mm	50 mm
03-254-017	Thermo Scientific™ 74204059270A	5 μm	20 mm	50 mm
03-254-018	Thermo Scientific™ 74204109070A	5 μm	10 mm	100 mm
03-254-019	Thermo Scientific™ 74204109270A	5 μm	20 mm	100 mm
03-254-020	Thermo Scientific™ 74204159070A	5 μm	10 mm	150 mm
03-254-021	Thermo Scientific™ 74204159270A	5 μm	20 mm	150 mm

Description

Improve conventional HPLC methods for your scale up purification needs by using Thermo Scientific™ Accucore™ XL C8 preparative HPLC columns. Rugged 4μm solid-core particles guarantee high-efficiencies within standard HPLC pressure limits. Our high coverage C8 bonded phase delivers optimal retention of analytes with moderate hydrophobicity. These columns come in a wide range of dimensions and an option for XtendedLife hardware which improves column lifetime by maintaining a uniform packed bed.

Lower Hydrophobic Retention

• Recommended for moderately hydrophobic analytes or when a less hydrophobic phase provides optimum retention.
• C8 (USP L7) selectivity.

High-Efficiency Separations for Enhanced Resolution and Sensitivity

• Core-enhanced technology 4μm particles and narrow particle size distribution reduce band broadening and improve separation efficiencies for conventional HPLC methods.
• High surface coverage of silica minimizes secondary interactions and peak tailing.

Preparative HPLC Column Hardware Options - based on column inner diameter (i.d.) and column performance needs.

Standard Threaded and Standard Flange Hardware

• Designed for standard applications, expertly packed and robustly designed to provide versatile products for routine use.
• Standard threaded hardware for column i.d. < 40mm.
• Standard flange hardware for column i.d. ≥ 40mm.
• Standard hardware can be modified on request to be compatible with SFC.

XtendedLife Hardware

• Improves column lifetime by incorporating an internal Dynamic Axial Compression (DAC) system, ensuring the media bed is continuously packed tightly.
• Compatible with SFC and is available in dimensions up to 50mm i.d.

Preparative Guards are a proven and cost effective way to extend the lifetime of your prep column. Our preparative guard columns require the use of a preparative guard holder.

Customer Specific Orders

• If there is a Thermo Scientific stationary phase you are currently using and would like to obtain in a preparative scale not shown or would like to discuss a specific column dimension, we would be happy to discuss your requirements.
• Please contact your local sales representative for Customer Specific Orders.
• Custom built columns are not eligible for returns.

Specifications

• Max. Pressure: 4300 psi (295 bar)
• pH: 2 to 9
• Surface Area: 90 m²/g
• USP Type: L7
• Packing Material: Spherical, Solid Core, Ultrapure Silica
• Column Type: Reversed Phase
• Phase: Reversed Phase

• Particle Size: 5 μm
• Pore Size: 80 Å
• Temperature: 60°C
• Stationary Phase: C8
• Carbon Load: 4%
• Endcapped: Yes