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A23187, free acid, Tocris Bioscience™

Catalog Number 123410
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Quantity:
10 mg
This item is not returnable. View return policy
52665-69-7
C29H37N3O6
523.63
MFCD00151202,MFCD00151202
HIYAVKIYRIFSCZ-CVXKHCKVSA-N
calcimycin, antibiotic a23187, ionophore a23187, calcium ionophore a23187, 4-benzoxazolecarboxylic acid, 5-methylamino-2-3,9,11-trimethyl-8-1-methyl-2-oxo-2-1h-pyrrol-2-yl ethyl-1,7-dioxaspiro 5.5 undec-2-yl methyl-, 6s-6alpha 2s*,3s* ,8beta r* ,9beta,11alpha, spectrum_001976, upcmld-dp093, upcmld-dp093:001, upcmld-dp093:002, upcmld-dp093:003
97043288
5-(methylamino)-2-{[(2S,3S,8S,9R,11R)-3,9,11-trimethyl-8-[1-oxo-1-(1H-pyrrol-2-yl)propan-2-yl]-1,7-dioxaspiro[5.5]undecan-2-yl]methyl}-1,3-benzoxazole-4-carboxylic acid
CNC1=CC=C2OC(C[C@@H]3OC4(CC[C@@H]3C)O[C@H](C(C)C(=O)C3=CC=CN3)[C@H](C)C[C@H]4C)=NC2=C1C(O)=O
This item is not returnable. View return policy
52665-69-7
C29H37N3O6
523.63
MFCD00151202,MFCD00151202
HIYAVKIYRIFSCZ-CVXKHCKVSA-N
calcimycin, antibiotic a23187, ionophore a23187, calcium ionophore a23187, 4-benzoxazolecarboxylic acid, 5-methylamino-2-3,9,11-trimethyl-8-1-methyl-2-oxo-2-1h-pyrrol-2-yl ethyl-1,7-dioxaspiro 5.5 undec-2-yl methyl-, 6s-6alpha 2s*,3s* ,8beta r* ,9beta,11alpha, spectrum_001976, upcmld-dp093, upcmld-dp093:001, upcmld-dp093:002, upcmld-dp093:003
97043288
5-(methylamino)-2-{[(2S,3S,8S,9R,11R)-3,9,11-trimethyl-8-[1-oxo-1-(1H-pyrrol-2-yl)propan-2-yl]-1,7-dioxaspiro[5.5]undecan-2-yl]methyl}-1,3-benzoxazole-4-carboxylic acid
CNC1=CC=C2OC(C[C@@H]3OC4(CC[C@@H]3C)O[C@H](C(C)C(=O)C3=CC=CN3)[C@H](C)C[C@H]4C)=NC2=C1C(O)=O

Description

Calcium ionophore

Calcium ionophore that induces Ca2+-dependent cell death by increasing intracellular calcium concentration. Promotes intracelllular ROS generation and platelet particle formation (fragmentation) in vitro and in vivo. Can be used to induce autophagy in mammalian cells.
Quantity 10 mg
Formula Weight 523.63
Percent Purity >98%
Chemical Name or Material A23187, free acid

Safety and Handling

Recommended Storage Desiccate at +4°C
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