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  8. 5,5'-Dithiobis(2-nitrobenzoic acid), 99%, Thermo Scientific Chemicals

5,5'-Dithiobis(2-nitrobenzoic acid), 99%, Thermo Scientific Chemicals

Catalog Number AAA1433106
Click to view available options
Quantity:
1 g
5 g
25 g
69-78-3
C14H8N2O8S2
396.34
MFCD00007140
KIUMMUBSPKGMOY-UHFFFAOYSA-N
dtnb, 5,5'-dithiobis 2-nitrobenzoic acid, ellman's reagent, 3-carboxy-4-nitrophenyl disulfide, dithionitrobenzoic acid, dithiobisnitrobenzoic acid, 5,5'-disulfanediylbis 2-nitrobenzoic acid, benzoic acid, 3,3'-dithiobis 6-nitro, 3,3'-dithiobis 6-nitrobenzoic acid, 5,5'-dithio-bis 2-nitrobenzoic acid
6254
CHEBI:86228
5-[(3-carboxy-4-nitrophenyl)disulfanyl]-2-nitrobenzoic acid
OC(=O)C1=CC(SSC2=CC=C(C(=C2)C(O)=O)[N+]([O-])=O)=CC=C1[N+]([O-])=O
69-78-3
C14H8N2O8S2
396.34
MFCD00007140
KIUMMUBSPKGMOY-UHFFFAOYSA-N
dtnb, 5,5'-dithiobis 2-nitrobenzoic acid, ellman's reagent, 3-carboxy-4-nitrophenyl disulfide, dithionitrobenzoic acid, dithiobisnitrobenzoic acid, 5,5'-disulfanediylbis 2-nitrobenzoic acid, benzoic acid, 3,3'-dithiobis 6-nitro, 3,3'-dithiobis 6-nitrobenzoic acid, 5,5'-dithio-bis 2-nitrobenzoic acid
6254
CHEBI:86228
5-[(3-carboxy-4-nitrophenyl)disulfanyl]-2-nitrobenzoic acid
OC(=O)C1=CC(SSC2=CC=C(C(=C2)C(O)=O)[N+]([O-])=O)=CC=C1[N+]([O-])=O

Description

Reagent for determination of sufhydryl groups.5,5'-dithiobis-(2-nitrobenzoic acid) is widely utilized as a non-fluorescent probe to quantify the number or the concentration of thiol groups in a sample. It acts as a cleavable cross-linking agent. It finds an important application as a sensitive reagent for determining free sulfhydryl content in proteins, peptides, and tissues. It is also employed in high-performance liquid chromatography (HPLC) to determine the alkylthiol content.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Reagent for determination of sufhydryl groups.5,5′-dithiobis-(2-nitrobenzoic acid) is widely utilized as a non-fluorescent probe to quantify the number or the concentration of thiol groups in a sample. It acts as a cleavable cross-linking agent. It finds an important application as a sensitive reagent for determining free sulfhydryl content in proteins, peptides, and tissues. It is also employed in high-performance liquid chromatography (HPLC) to determine the alkylthiol content.

Solubility
Soluble in water and ethanol.

Notes
Keep the container tightly closed in a dry and well-ventilated place. Incompatible with strong oxidizing agents and strong bases.
TRUSTED_SUSTAINABILITY
Melting Point ∼240°C (decomposition)
Quantity 5 g
Beilstein 1896821
Solubility Information Soluble in water and ethanol.
Formula Weight 396.36
Percent Purity 99%
Chemical Name or Material 5,5'-Dithiobis(2-nitrobenzoic acid)

Safety and Handling

Hazard Category H315-H319-H335
Hazard Statement GHS H Statement
H315-H319-H335
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.
Precautionary Statement P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P362-P501c
EINECSNumber 200-714-4
RTECSNumber DG9650000
TSCA Yes
Recommended Storage Ambient temperatures
SDS

RUO – Research Use Only

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