4,4'-Diaminodiphenyl sulfone, 98%, Thermo Scientific Chemicals

Description

It is active against a wide range of bacteria, but is mainly employed for its actions against Mycobacterium leprae, being used as part of multidrug regimens in the treatment of all forms of leprosy. It is a second-line medication for the treatment and prevention of Pneumocystis pneumonia and for the prevention of toxoplasmosis in those who have poor immune function. Additionally, it has been used for acne as well as other skin conditions. Moreover it is employed as an anti-inflammatory drug, anti-infective drug, a leprostatic drug and an antimalarial drug.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Solubility
Insoluble in water. Solubility in hot methanol is almost transparent. Soluble in DMSO, ethanol and acetone.

Notes
Store away from oxidizing agents. Keep the container tightly closed and place it in a cool, dry and well ventilated condition.

Specifications

Chemical Identifiers

• CAS: 80-08-0
• Molecular Formula: C12H12N2O2S
• Molecular Weight (g/mol): 248.3
• MDL Number: MFCD00007887
• InChI Key: MQJKPEGWNLWLTK-UHFFFAOYSA-N
• Synonym: dapsone, diaphenylsulfone, 4,4'-diaminodiphenyl sulfone, dapson, 4,4'-sulfonyldianiline, diaphenylsulfon, sulfona, 4-aminophenyl sulfone, avlosulfone, diphenasone
• PubChem CID: 2955
• ChEBI: CHEBI:4325
• IUPAC Name: 4-(4-aminophenyl)sulfonylaniline
• SMILES: C1=CC(=CC=C1N)S(=O)(=O)C2=CC=C(C=C2)N

• Melting Point: 175°C to 178°C
• Odor: Odorless
• Quantity: 500 g
• Beilstein: 788055
• Merck Index: 14,2822
• Solubility Information: Insoluble in water. Solubility in hot methanol is almost transparent. Soluble in DMSO,ethanol and acetone.
• Formula Weight: 248.3
• Percent Purity: 98%
• Chemical Name or Material: 4,4'-Diaminodiphenyl sulfone

Safety and Handling

Hazard Category	H302-H373
Hazard Statement	GHS H Statement H302 Harmful if swallowed.
Precautionary Statement	P260-P264b-P270-P301+P312-P314-P330-P501c
EINECSNumber	201-248-4
RTECSNumber	BY8925000
TSCA	Yes
Recommended Storage	Ambient temperatures

SDS

RUO – Research Use Only