Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Chemicals
  4. Organic compounds
  5. Organoheterocyclic compounds
  6. Pyrrolopyrimidines
  7. 3-MPPI, Tocris Bioscience™

3-MPPI, Tocris Bioscience™

Catalog No. 058150
Click to view available options
Quantity:
10 mg
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

α1 ligand

Very potent ligand for α1 sites (Ki for displacement of prazosin = 0.2 nM). Displays different binding properties for each α1 subtype (pKi values are 8.74, 9.44 and 9.57 for α1B, α1D and α1A adrenoceptors respectively). Also binds to 5-HT1A sites (Ki = 50 nM).

Chemical Identifiers

CAS 133399-65-2
Molecular Formula C23H25N5O3
Molecular Weight (g/mol) 419.485
InChI Key AQASGOHUMGAWJJ-UHFFFAOYSA-N
Synonym 3-mppi, tocris-0581, biomol-nt_000127, 3-2-4-2-methoxyphenyl piperazino ethyl-1h-pyrimido 5,4-b indole-2,4 3h,5h-dione, 2-2-4-2-methoxy-phenyl-piperazin-1-yl-ethyl-4,9-dihydro-2,4,9-triaza-fluorene-1,3-dione, 3-2-4-2-methoxyphenyl piperazin-1-yl ethyl-1h-pyrimido 5,4-b indole-2,4 3h,5h-dione, 3-2-4-2-methoxyphenyl piperazin-1-yl ethyl-1,5-dihydropyrimido 5,4-b indole-2,4-dione, 3-2-4-2-methoxy-phenyl-piperazin-1-yl-ethyl-1,5-dihydro-pyrimido 5,4-b indole-2,4-dione
PubChem CID 4013695
IUPAC Name 3-[2-[4-(2-methoxyphenyl)piperazin-1-yl]ethyl]-1,5-dihydropyrimido[5,4-b]indole-2,4-dione
SMILES COC1=CC=CC=C1N2CCN(CC2)CCN3C(=O)C4=C(C5=CC=CC=C5N4)NC3=O

Specifications

Quantity 50 mg
Formula Weight 419.48
Percent Purity >98%
Chemical Name or Material 3-MPPI

Safety and Handling

Recommended Storage Store at Room Temperature
Product Content Correction

Your input is important to us. Please complete this form to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.