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3-Isobutyl-1-methylxanthine, Thermo Scientific Chemicals

Catalog Number AAJ64598MC
Click to view available options
Quantity:
100 mg
28822-58-4
C10H14N4O2
222.25
MFCD00005584
APIXJSLKIYYUKG-UHFFFAOYSA-N
3-isobutyl-1-methylxanthine, ibmx, isobutylmethylxanthine, 1-methyl-3-isobutylxanthine, methylisobutylxanthine, 3-isobutyl-1-methyl-1h-purine-2,6 3h,7h-dione, xanthine, 3-isobutyl-1-methyl, 3-isobutyl-1-methyxanthine, 1h-purine-2,6-dione, 3,7-dihydro-1-methyl-3-2-methylpropyl, methyl-isobutylxanthine
3758
CHEBI:43253
1-methyl-3-(2-methylpropyl)-7H-purine-2,6-dione
CC(C)CN1C2=C(NC=N2)C(=O)N(C)C1=O
28822-58-4
C10H14N4O2
222.25
MFCD00005584
APIXJSLKIYYUKG-UHFFFAOYSA-N
3-isobutyl-1-methylxanthine, ibmx, isobutylmethylxanthine, 1-methyl-3-isobutylxanthine, methylisobutylxanthine, 3-isobutyl-1-methyl-1h-purine-2,6 3h,7h-dione, xanthine, 3-isobutyl-1-methyl, 3-isobutyl-1-methyxanthine, 1h-purine-2,6-dione, 3,7-dihydro-1-methyl-3-2-methylpropyl, methyl-isobutylxanthine
3758
CHEBI:43253
1-methyl-3-(2-methylpropyl)-7H-purine-2,6-dione
CC(C)CN1C2=C(NC=N2)C(=O)N(C)C1=O

Description

 

3-Isobutyl-1-methylxanthine is used in inhibition of phenylephrine-induced release of 5-hydroxytryptamine from neuroendocrine epithelial cells of the airway mucosa (IC50 = 1.3 uM). Also inhibits ion channels in the neuromuscular junction, GH3 cells, and vascular smooth muscle cells. Inhibits the growth of carcinoma cells.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
3-Isobutyl-1-methylxanthine is used in inhibition of phenylephrine-induced release of 5-hydroxytryptamine from neuroendocrine epithelial cells of the airway mucosa (IC50 = 1.3 uM). Also inhibits ion channels in the neuromuscular junction.
TRUSTED_SUSTAINABILITY
Melting Point 200°C to 201°C
Quantity 100 mg
Solubility Information Soluble in ethanol.
Formula Weight 222.24
Physical Form Solid
Chemical Name or Material 3-Isobutyl-1-methylxanthine

Safety and Handling

Hazard Category H302
Hazard Statement GHS H Statement
H302
Harmful if swallowed.
Precautionary Statement P264b-P270-P301+P312-P330-P501c
EINECSNumber 249-259-3
RTECSNumber ZD8500000
TSCA No
Recommended Storage Store at -20°C
SDS

RUO – Research Use Only

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