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  6. Thermo Scientific Chemicals 3'-Azido-3'-deoxythymidine, 98%

Thermo Scientific Chemicals 3'-Azido-3'-deoxythymidine, 98%

Catalog Number AAJ6512703
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Quantity:
1 g
5 g
25 g
30516-87-1
C10H13N5O4
267.25
MFCD00006536
HBOMLICNUCNMMY-CFQLRCIDNA-N
azt; azidothymidine; zdv; zidovudine, 1-2r-4-azido-5-hydroxymethyl oxolan-2-yl-5-methyl-3h-pyrimidine-2,4-dione
455007
CC1=CN([C@H]2C[C@H](N=[N+]=[N-])[C@@H](CO)O2)C(=O)NC1=O
30516-87-1
C10H13N5O4
267.25
MFCD00006536
HBOMLICNUCNMMY-CFQLRCIDNA-N
azt; azidothymidine; zdv; zidovudine, 1-2r-4-azido-5-hydroxymethyl oxolan-2-yl-5-methyl-3h-pyrimidine-2,4-dione
455007
CC1=CN([C@H]2C[C@H](N=[N+]=[N-])[C@@H](CO)O2)C(=O)NC1=O

Description

Anti-viral agent

3'-Azido-3'-deoxythymidine is a Anti-viral agent, and also used as a reverse transcriptase inhibitor active against HIV-1 virus that blocks the incorporation of nucleotides into growing DNA strands. Useful for antiviral and anticancer studies. 3?-Azido-3?-deoxythymidine enters CNS by diffusion and causes irreversible telomere shortening.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
3′-Azido-3′-deoxythymidine is a Anti-viral agent, and also used as a reverse transcriptase inhibitor active against HIV-1 virus that blocks the incorporation of nucleotides into growing DNA strands. Useful for antiviral and anticancer studies. 3′-Azido-3′-deoxythymidine enters CNS by diffusion and causes irreversible telomere shortening.

Solubility
Soluble in water.

Notes
Light Sensitive & Hygroscopic. Keep container tightly closed. Store in cool, dry conditions in well sealed containers.
TRUSTED_SUSTAINABILITY
Melting Point 113°C to 115°C
Color White
Quantity 1 g
Beilstein 3595791
Sensitivity Light sensitive; Very Hygroscopic
Merck Index 1410123
Solubility Information Soluble in water.
IUPAC Name 1-[(2R,5S)-4-azido-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione
Formula Weight 267.24
Percent Purity 98%
Physical Form Powder
Chemical Name or Material 3'-Azido-3'-deoxythymidine
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Safety and Handling

Hazard Category Serious eye damage/eye irritation (category 2), Germ cell mutagenicity (category 2), Specific target organ toxicity after single exposure (category 3), Carcinogenicity (category 2), Skin corrosion/irritation (category 2)
Hazard Statement Causes serious eye irritation, Suspected of causing genetic defects, May cause respiratory irritation, Suspected of causing cancer, Causes skin irritation
RTECSNumber XP207200
TSCA No
Recommended Storage Store at -20°C
SDS

RUO – Research Use Only

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