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  7. 2-Mercapto-1-methylimidazole, 98%, Thermo Scientific Chemicals

2-Mercapto-1-methylimidazole, 98%, Thermo Scientific Chemicals

Catalog Number AC125501000
Click to view available options
Quantity:
25 g
100 g
500 g
Packaging:
Glass bottle
60-56-0
C4H6N2S
114.17
MFCD00179321
PMRYVIKBURPHAH-UHFFFAOYSA-N
methimazole, thiamazole, 2-mercapto-1-methylimidazole, tapazole, mercazolyl, 1-methylimidazole-2-thiol, mercazole, metazolo, methimazol, thiamazol
1349907
CHEBI:50673
3-methyl-1H-imidazole-2-thione
CN1C=CNC1=S
60-56-0
C4H6N2S
114.17
MFCD00179321
PMRYVIKBURPHAH-UHFFFAOYSA-N
methimazole, thiamazole, 2-mercapto-1-methylimidazole, tapazole, mercazolyl, 1-methylimidazole-2-thiol, mercazole, metazolo, methimazol, thiamazol
1349907
CHEBI:50673
3-methyl-1H-imidazole-2-thione
CN1C=CNC1=S

Description

2-Mercapto-1-methylimidazole, CAS # 60-56-0, also known as methimazole, is a thyroid hormone antagonist used to study the treatment of thyroid disorders.

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description
• 2-Mercapto-1-methylimidazole, also known as methimazole, is an antithyroid medication
• Methimazole works by inhibiting the enzyme thyroid peroxidase (TPO), which is responsible for synthesizing the thyroid hormones triiodothyronine (T3) and thyroxine (T4) from the precursor thyroglobulin
Applications
• Methimazole has been used in laboratory settings to model olfactory epithelial degeneration
• May be used to study disruptions in iodide metabolism
• Methimazole has been used in Pharmacokinetics studies in the laboratory
TRUSTED_SUSTAINABILITY
Melting Point 140.0°C to 145.0°C
Color Cream to White
Boiling Point 280.0°C
Flash Point >100°C
Loss on Drying 1% (105°C, 2 hrs) max.
Infrared Spectrum Authentic
Assay Percent Range 98%
Packaging Glass bottle
Quantity 100 g
Beilstein 24,17
Merck Index 15,6043
Solubility Information Solubility in water: soluble. Other solubilities: soluble in ethanol and acetone,sparingly soluble in ether,petr. ether,benzene
Formula Weight 114.16
Percent Purity 98%
Physical Form Crystalline Powder
Chemical Name or Material 2-Mercapto-1-methylimidazole
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Safety and Handling

Hazard Category GHS Signal Word: Warning
Hazard Statement GHS H Statement
May cause an allergic skin reaction.
Suspected of damaging fertility.
Suspected of damaging the unborn child.
Precautionary Statement GHS P Statement
Wear eye protection/face protection.
Use personal protective equipment as required.
Avoid breathing dust/fume/gas/mist/vapors/spray.
Contaminated work clothing should not be allowed out of the workplace.
EINECSNumber 200-482-4
SDS

RUO – Research Use Only

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