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  7. 1-Boc-piperazine, 99%, Thermo Scientific Chemicals

1-Boc-piperazine, 99%, Thermo Scientific Chemicals

Catalog Number AAL1336306
Click to view available options
Quantity:
1 g
5 g
25 g
57260-71-6
C9H19N2O2
187.26
MFCD00075265
CWXPZXBSDSIRCS-UHFFFAOYSA-O
1-boc-piperazine, n-boc-piperazine, 1-n-boc-piperazine, tert-butyl 1-piperazinecarboxylate, 1-tert-butoxycarbonyl piperazine, n-t-butoxycarbonylpiperazine, boc-piperazine, n-tert-butoxycarbonylpiperazine, piperazine-1-carboxylic acid tert-butyl ester, 1-piperazinecarboxylic acid, 1,1-dimethylethyl ester
143452
tert-butyl piperazine-1-carboxylate
CC(C)(C)OC(=O)N1CC[NH2+]CC1
57260-71-6
C9H19N2O2
187.26
MFCD00075265
CWXPZXBSDSIRCS-UHFFFAOYSA-O
1-boc-piperazine, n-boc-piperazine, 1-n-boc-piperazine, tert-butyl 1-piperazinecarboxylate, 1-tert-butoxycarbonyl piperazine, n-t-butoxycarbonylpiperazine, boc-piperazine, n-tert-butoxycarbonylpiperazine, piperazine-1-carboxylic acid tert-butyl ester, 1-piperazinecarboxylic acid, 1,1-dimethylethyl ester
143452
tert-butyl piperazine-1-carboxylate
CC(C)(C)OC(=O)N1CC[NH2+]CC1

Description

1-Boc-piperazine is useful for the preparation of (m-phenoxy)phenyl substituted piperazine derivatives. It is also used in the synthesis of indazole DNA gyrase inhibitors. Further, it plays an important role in the preparation of alfa,beta-poly(2-oxazoline) lipopolymers through living cationic ring opening polymerization. It is also in involved in Buchwald-Hartwig coupling reactions with aryl halides.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
1-Boc-piperazine is useful for the preparation of (m-phenoxy)phenyl substituted piperazine derivatives. It is also used in the synthesis of indazole DNA gyrase inhibitors. Further, it plays an important role in the preparation of alfa,beta-poly(2-oxazoline) lipopolymers through living cationic ring opening polymerization. It is also in involved in Buchwald-Hartwig coupling reactions with aryl halides.

Solubility
Soluble in ethyl acetate, methanol and water.

Notes
Hygroscopic. Store in a cool place. Moisture sensitive. Incompatible with strong oxidizing agents.
TRUSTED_SUSTAINABILITY
Melting Point 44°C to 48°C
Quantity 5 g
Beilstein 879985
Sensitivity Air Sensitive
Solubility Information Soluble in ethyl acetate,methanol and water.
Formula Weight 186.26
Percent Purity 99%
Chemical Name or Material 1-Boc-piperazine

Safety and Handling

Hazard Category H315-H319-H335
Hazard Statement GHS H Statement
H315-H319-H335
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.
Precautionary Statement P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P362-P501c
TSCA No
Recommended Storage Ambient temperatures; Store under Nitrogen
SDS

RUO – Research Use Only

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