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  7. 1,1-Dimethylbiguanide Hydrochloride, MP Biomedicals™

1,1-Dimethylbiguanide Hydrochloride, MP Biomedicals™

Catalog Number MP215780525
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Quantity:
25 g
100 g
1115-70-4
C4H12ClN5
165.63
MFCD00012582
OETHQSJEHLVLGH-UHFFFAOYSA-N
hydrogen 1-[(diaminomethylidene)amino]-N,N-dimethylmethanimidamide chloride
[H+].[Cl-].CN(C)C(=N)N=C(N)N
1115-70-4
C4H12ClN5
165.63
MFCD00012582
OETHQSJEHLVLGH-UHFFFAOYSA-N
hydrogen 1-[(diaminomethylidene)amino]-N,N-dimethylmethanimidamide chloride
[H+].[Cl-].CN(C)C(=N)N=C(N)N

Description

1,1-Dimethylbiguanide Hydrochloride, White Powder

  • It has various medical uses such as in polycystic ovary syndrome, non-alcoholic fatty liver disease and diabetes mellitus type 2.
  • It may also reduce weight gain in people taking atypical antipsychotics. 1,1-Dimethylbiguanide hydrochloride is suitable biguanide agent used in a study to investigate its role in enhancing the secretions of plasma active glucagon-like peptide-1 (GLP-1) levels.
  • 1,1-Dimethylbiguanide, Hydrochloride (Metformin) is a biguanide antihyperglycemic agent. 1,1-Dimethylbiguanide hydrochloride (metformin) is a strong base.
  • It forms well defined salts and possessing excellent coordination capacity with transition metals, forming highly colored bidentate chelate complexes.
  • Metformin (MET) exists in various forms: diprotonated (H2MET)2+ in strong acidic solution, monoprotonated (HMET)+ in weak acid, MET in neutral and deprotonated (MET)- in strong alkali solution. It is an oral antidiabetic drug.
  • Pharmacokinetics of metformin has been studied. Determination of metformin in human plasma has been described by simple HPLC-UV method.[5] Metformin is reported to increase plasma active glucagon-like peptide-1 (GLP-1) in humans
Melting Point 214°C to 224°C
Color White
Quantity 25 g
Synonym N,N-Dimethylimidodicarbonimidic diamine, 1,1-Dimethylbiguanide hydrochloride, DMGG, LA-6023
Solubility Information Soluble in water (100mg/mL - clear, colorless solution), 95% ethanol; insoluble in ether, acetone or chloroform.
Physical Form Powder

Safety and Handling

RTECSNumber DU1800000
storageNote1 Store at Room Temperature (15-30°C).
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