Mm00737181_cn

• Gene Symbol: Nkx3-1
• Assay Reference Genome Location: Chr.14:69191437 on build GRCm38
• Cytoband: 14D2

Target Gene Details

• Entrez Gene ID: 18095
• Gene Name: NK-3 transcription factor, locus 1 (Drosophila)
• Gene Aliases: Bax, NKX3.1, NKX3A, Nkx-3.1, bagpipe
• Location: Chr.14:69190692-69194658 on Build GRCm38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
Nkx3-1	NM_010921.3			NP_035051.1
	AK137281.1			BAE23291.1
	BC132401.1
	BC132427.1
	U73460.1			AAC52956.1
	U88542.1			AAB58025.1

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, Validated

Panther Classification:

Molecular Function -

homeodomain transcription factor

Gene Ontology Categories:

Process(es)

urogenital system development
positive regulation of protein phosphorylation
transcription, DNA-templated
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
activation of cysteine-type endopeptidase activity involved in apoptotic process
multicellular organism development
salivary gland development
positive regulation of cell proliferation
negative regulation of cell proliferation
positive regulation of gene expression
negative regulation of gene expression
positive regulation of cell death
positive regulation of phosphatidylinositol 3-kinase signaling
androgen receptor signaling pathway
prostate gland development
response to testosterone
internal genitalia morphogenesis
positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
steroid hormone mediated signaling pathway
protein kinase B signaling
negative regulation of insulin-like growth factor receptor signaling pathway
positive regulation of protein kinase activity
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
negative regulation of mitotic cell cycle
positive regulation of mitotic cell cycle
positive regulation of transcription from RNA polymerase II promoter
branching morphogenesis of an epithelial tube
negative regulation of epithelial cell proliferation
positive regulation of cell division
branching involved in prostate gland morphogenesis
epithelial cell proliferation involved in salivary gland morphogenesis
negative regulation of epithelial cell proliferation involved in prostate gland development
cellular response to steroid hormone stimulus
cellular response to hypoxia
mitotic cell cycle arrest
negative regulation of estrogen receptor binding
positive regulation of androgen secretion
positive regulation of response to DNA damage stimulus
positive regulation of apoptotic signaling pathway
positive regulation of intrinsic apoptotic signaling pathway

Function(s)

transcription regulatory region sequence-specific DNA binding
transcription factor activity, RNA polymerase II core promoter sequence-specific
core promoter binding
DNA binding
transcription factor activity, sequence-specific DNA binding
androgen receptor activity
protein binding
transcription factor binding
cysteine-type endopeptidase activator activity involved in apoptotic process
estrogen receptor activity
protein kinase activator activity
estrogen receptor binding
histone deacetylase binding
sequence-specific DNA binding
protein self-association
transcription regulatory region DNA binding
MADS box domain binding