Mm00601355_cn

• Gene Symbol: Itk
• Assay Reference Genome Location: Chr.11:46326732 on build GRCm38
• Cytoband: 11B1.1

Target Gene Details

• Entrez Gene ID: 16428
• Gene Name: IL2 inducible T cell kinase
• Gene Aliases: Emt, Tcsk, Tsk
• Location: Chr.11:46325148-46389515 on Build GRCm38
• Assay Gene Location: Within Exon 18

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
Itk	NM_001281965.1	17	2708	NP_001268894.1
	NM_001281966.1	17	2699	NP_001268895.1
	NM_001281968.1	17	2687	NP_001268897.1
	NM_010583.3	17	2690	NP_034713.2
	AK083380.1	17	2662
	AK153613.1	17	2646	BAE32118.1
	D14042.1	17	2630	BAA03129.1
	L00619.1	17	2695	AAA39337.1
	L05631.1	17	2656	AAA40518.1

More Information

• Set Membership: Intragenic, Exonic

Gene Ontology Categories:

Process(es)

cytokine production
NK T cell differentiation
adaptive immune response
immune system process
protein phosphorylation
transmembrane receptor protein tyrosine kinase signaling pathway
activation of phospholipase C activity
phosphorylation
peptidyl-tyrosine phosphorylation
interferon-gamma production
interleukin-4 production
intracellular signal transduction
peptidyl-tyrosine autophosphorylation
regulation of cell proliferation
innate immune response
T cell receptor signaling pathway

Function(s)

nucleotide binding
protein kinase activity
protein tyrosine kinase activity
non-membrane spanning protein tyrosine kinase activity
protein binding
ATP binding
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
metal ion binding