Mm00587523_cn

• Gene Symbol: Tirap
• Assay Reference Genome Location: Chr.9:35188759 on build GRCm38
• Cytoband: 9A4

Target Gene Details

• Entrez Gene ID: 117149
• Gene Name: toll-interleukin 1 receptor (TIR) domain-containing adaptor protein
• Gene Aliases: AA407980, C130027E04Rik, Mal, Tlr4ap, Wyatt
• Location: Chr.9:35184391-35200291 on Build GRCm38
• Assay Gene Location: Within Exon 7

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
Tirap	NM_001177845.1	6	1107	NP_001171316.1
	NM_001177846.1	6	1089	NP_001171317.1
	NM_001177847.1	6	1035	NP_001171318.1
	NM_054096.2	6	1099	NP_473437.2
	AF378130.1	6	1008	AAL05628.1
	AF410784.1	5	931	AAL05037.1
	AK036431.1	6	1028	BAC29426.1
	AK080135.1	6	1108	BAC37831.1
	AK151117.1	6	1037	BAE30126.1
	AK168494.1	6	1027	BAE40381.1
	BC005584.1	3	765	AAH05584.1

More Information

• Set Membership: Intragenic, Exonic

Gene Ontology Categories:

Process(es)

immune system process
inflammatory response
signal transduction
cell surface receptor signaling pathway
I-kappaB kinase/NF-kappaB signaling
activation of JUN kinase activity
response to bacterium
myeloid cell differentiation
positive regulation of B cell proliferation
response to lipopolysaccharide
regulation of interferon-beta production
regulation of interleukin-15 production
positive regulation of interleukin-12 production
positive regulation of interleukin-15 production
positive regulation of interleukin-8 production
positive regulation of tumor necrosis factor production
positive regulation of toll-like receptor 2 signaling pathway
positive regulation of toll-like receptor 3 signaling pathway
positive regulation of toll-like receptor 4 signaling pathway
toll-like receptor 5 signaling pathway
TIRAP-dependent toll-like receptor 4 signaling pathway
positive regulation of I-kappaB kinase/NF-kappaB signaling
negative regulation of growth of symbiont in host
innate immune response
regulation of innate immune response
positive regulation of innate immune response
positive regulation of interleukin-6 biosynthetic process
positive regulation of JNK cascade
defense response to Gram-positive bacterium
positive regulation of NF-kappaB transcription factor activity
positive regulation of ERK1 and ERK2 cascade
interleukin-1-mediated signaling pathway
3'-UTR-mediated mRNA stabilization
cellular response to bacterial lipopeptide
cellular response to lipoteichoic acid
positive regulation of neutrophil chemotaxis
positive regulation of protein homodimerization activity
positive regulation of chemokine (C-X-C motif) ligand 1 production
positive regulation of chemokine (C-X-C motif) ligand 2 production

Function(s)

protein kinase C binding
protein binding
phosphatidylinositol-4,5-bisphosphate binding
Toll-like receptor 4 binding
Toll-like receptor 2 binding
protein homodimerization activity
protein heterodimerization activity