Mm00573345_cn

• Gene Symbol: Ercc2
• Assay Reference Genome Location: Chr.7:19395470 on build GRCm38
• Cytoband: 7A3

Target Gene Details

• Entrez Gene ID: 13871
• Gene Name: excision repair cross-complementing rodent repair deficiency, complementation group 2
• Gene Aliases: AA407812, AU020867, AW240756, CXPD, Ercc-2, XPD
• Location: Chr.7:19382039-19395692 on Build GRCm38
• Assay Gene Location: Within Exon 23

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
Ercc2	NM_007949.4	23	3325	NP_031975.2
	AK004652.1	19	2977	BAB23443.1
	AK082323.1	16	2579
	AK082761.1	23	3326	BAC38607.1
	AK141692.1	23	3343
	AK145969.1	23	3334	BAE26794.1
	BC034517.1	22	3261	AAH34517.1

Target Gene Details

• Entrez Gene ID: 232943
• Gene Name: kinesin light chain 3
• Gene Aliases: BC017147, Klct
• Location: Chr.7:19394440-19404442 on Build GRCm38
• Assay Gene Location: Overlaps Intron 9 - Exon 10

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
Klc3	NM_001286038.1			NP_001272967.1
	NM_001286039.1			NP_001272968.1
	NM_146182.4			NP_666294.1
	AK158094.1			BAE34354.1
	BC017147.1			AAH17147.1

More Information

• Set Membership: Intragenic, Exonic, Non-exonic

Panther Classification:

Molecular Function -

DNA helicase, cytoskeletal protein, microtubule binding motor protein, microtubule or microtubule-binding cytoskeletal protein

Gene Ontology Categories:

Process(es)

in utero embryonic development
nucleobase-containing compound metabolic process
DNA repair
transcription-coupled nucleotide-excision repair
nucleotide-excision repair
transcription, DNA-templated
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
protein phosphorylation
apoptotic process
cellular response to DNA damage stimulus
response to oxidative stress
chromosome segregation
aging
cell proliferation
response to UV
UV protection
post-embryonic development
spinal cord development
hair cycle process
extracellular matrix organization
bone mineralization
central nervous system myelin formation
DNA duplex unwinding
nucleotide-excision repair, DNA incision
multicellular organism growth
hair cell differentiation
embryonic cleavage
erythrocyte maturation
positive regulation of DNA binding
skin development
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
hair follicle maturation
hematopoietic stem cell differentiation
regulation of mitotic cell cycle phase transition
axo-dendritic transport
intraciliary transport

Function(s)

nucleotide binding
nucleic acid binding
DNA binding
ATP-dependent DNA helicase activity
helicase activity
protein kinase activity
ATP binding
protein C-terminus binding
ATP-dependent helicase activity
DNA-dependent ATPase activity
RNA polymerase II carboxy-terminal domain kinase activity
hydrolase activity
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
5'-3' DNA helicase activity
metal ion binding
protein N-terminus binding
iron-sulfur cluster binding
4 iron, 4 sulfur cluster binding
microtubule motor activity
protein binding
microtubule binding
kinesin binding