Mm00363138_cn

• Gene Symbol: Srebf1
• Assay Reference Genome Location: Chr.11:60202846 on build GRCm38
• Cytoband: 11B2

Target Gene Details

• Entrez Gene ID: 20787
• Gene Name: sterol regulatory element binding transcription factor 1
• Gene Aliases: ADD-1, ADD1, D630008H06, SREBP-1, SREBP-1a, SREBP-1c, SREBP1, SREBP1c, bHLHd1
• Location: Chr.11:60199089-60222686 on Build GRCm38
• Assay Gene Location: Within Exon 12

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
Srebf1	NM_011480.3	12	2327	NP_035610.1
	AF374266.1	11	2091	AAK54762.1
	AK052628.1	12	2328	BAC35068.1
	AK150052.1	12	2316	BAE29268.1
	AK154424.1	12	2295	BAE32576.1
	AK158269.1	5	876	BAE34440.1
	AK169607.1	12	2328	BAE41256.1
	AK198337.1	1	41
	BC006051.1	9	1463	AAH06051.1
	BC056922.1	12	2309	AAH56922.1

More Information

• Set Membership: Intragenic, Exonic

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
regulation of heart rate by chemical signal
transcription, DNA-templated
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
lipid metabolic process
steroid metabolic process
cholesterol metabolic process
insulin receptor signaling pathway
lipid biosynthetic process
cellular response to starvation
response to glucose
positive regulation of triglyceride biosynthetic process
regulation of fatty acid metabolic process
positive regulation of histone deacetylation
regulation of protein stability
positive regulation of cholesterol biosynthetic process
positive regulation of fatty acid biosynthetic process
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
negative regulation of insulin secretion
regulation of insulin secretion
regulation of mitophagy
regulation of protein targeting to mitochondrion

Function(s)

RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
DNA binding
chromatin binding
transcription factor activity, sequence-specific DNA binding
protein binding
protein kinase binding
protein complex binding
sterol response element binding
sequence-specific DNA binding
transcription regulatory region DNA binding
protein dimerization activity