Hs06972530_cn

• Gene Symbol: AICDA
• Assay Reference Genome Location: Chr.12:8609159 on build GRCh38
• Cytoband: 12p13.31

Target Gene Details

• Entrez Gene ID: 57379
• Gene Name: activation-induced cytidine deaminase
• Gene Aliases: AID, ARP2, CDA2, HEL-S-284, HIGM2
• Location: Chr.12:8602166-8612970 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
AICDA	NM_020661.2			NP_065712.1
	XM_011520772.2			XP_011519074.1
	XM_011520773.2			XP_011519075.1
	AB040431.1			BAB12721.1
	BC006296.2			AAH06296.1
	BX402063.2
	EU794587.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1051530	Chr.12:8442286 - 9951690 on Build GRCh38	Gain	LOC105369649 KLRG1 M6PR LOC105376678 LOC105369728 MIR1244-3 CLEC2A OVOS KLRB1 KLRF2 MFAP5 LINC00612 AICDA CLEC4E A2M CLEC6A CLEC2B PZP CLEC12A LOC374443 PHC1 CLEC4D LOC642846 KLRF1 CLEC2D CD69 LOC101928030 LOC400002 LOC101930452 CLECL1 DDX12P A2MP1 A2M-AS1 RIMKLB LOC100506159 LINC00987 LOC728715 A2ML1
nsv557342	Chr.12:8446801 - 8621931 on Build GRCh38	Loss	AICDA CLEC4D CLEC4E CLEC6A
dgv1362n100	Chr.12:8296504 - 8639973 on Build GRCh38	Gain	AICDA CLEC4D CLEC4E CLEC6A LINC00937

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

RNA processing factor

Gene Ontology Categories:

Process(es)

mRNA processing
cytidine deamination
somatic diversification of immunoglobulins
somatic hypermutation of immunoglobulin genes
B cell differentiation
isotype switching
cellular response to lipopolysaccharide
DNA demethylation
negative regulation of methylation-dependent chromatin silencing

Function(s)

cytidine deaminase activity
protein binding
zinc ion binding
ubiquitin protein ligase binding