Hs06730733_cn

• Gene Symbol: TCF7
• Assay Reference Genome Location: Chr.5:134119821 on build GRCh38
• Cytoband: 5q31.1

Target Gene Details

• Entrez Gene ID: 6932
• Gene Name: transcription factor 7 (T-cell specific, HMG-box)
• Gene Aliases: TCF-1
• Location: Chr.5:134114703-134148229 on Build GRCh38
• Assay Gene Location: Within Intron 3

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
TCF7	NM_001134851.2			NP_001128323.2
	NM_003202.3			NP_003193.2
	NM_201632.3			NP_963963.1
	NM_201634.3			NP_963965.1
	NM_213648.3			NP_998813.1
	NR_033449.1
	XM_006714678.3			XP_006714741.1
	XM_006714679.3			XP_006714742.1
	XM_006714680.3			XP_006714743.1
	XM_006714682.2			XP_006714745.1
	XM_006714684.2			XP_006714747.1
	XM_006714685.3			XP_006714748.1
	XM_006714686.3			XP_006714749.1
	XM_011543604.2			XP_011541906.1
	XM_011543606.1			XP_011541908.1
	XM_011543610.2			XP_011541912.1
	XM_011543613.2			XP_011541915.1
	XM_017009789.1			XP_016865278.1
	AK057580.1
	AK093530.1
	AL832816.1
	AL834166.1
	BC048769.1			AAH48769.1
	BC072023.1			AAH72023.1
	DA627229.1
	DB137814.1
	DB145426.1
	X59869.1			CAA42526.1
	X59870.1			CAA42527.1
	X59871.1			CAA42528.1
	Z47361.1			CAA87439.1
	Z47362.1			CAA87440.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv599732	Chr.5:134099223 - 134230401 on Build GRCh38	Loss	MIR3661 TCF7 PPP2CA SKP1

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

DNA-binding transcription factor

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
immune response
neural tube development
embryonic genitalia morphogenesis
T cell receptor V(D)J recombination
regulation of cell proliferation
canonical Wnt signaling pathway involved in negative regulation of apoptotic process
alpha-beta T cell differentiation
embryonic digestive tract morphogenesis
embryonic hindgut morphogenesis
canonical Wnt signaling pathway
cellular response to interleukin-4
beta-catenin-TCF complex assembly

Function(s)

core promoter binding
transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding
protein binding
beta-catenin binding
sequence-specific DNA binding
transcription regulatory region DNA binding