Hs06656984_cn

• Gene Symbol: POU1F1
• Assay Reference Genome Location: Chr.3:87261584 on build GRCh38
• Cytoband: 3p11.2

Target Gene Details

• Entrez Gene ID: 5449
• Gene Name: POU class 1 homeobox 1
• Gene Aliases: CPHD1, GHF-1, PIT1, POU1F1a, Pit-1
• Location: Chr.3:87259633-87276587 on Build GRCh38
• Assay Gene Location: Within Intron 4

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
POU1F1	NM_000306.3			NP_000297.1
	NM_001122757.2			NP_001116229.1
	D10216.1			BAA01068.1
	L18781.1			AAA60093.1
	X62429.1			CAA44295.1
	X72215.1			CAA51017.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv3568885	Chr.3:87182571 - 87518398 on Build GRCh38	Loss	MIR4795 CHMP2B POU1F1
nsv527279	Chr.3:86796784 - 87814130 on Build GRCh38	Gain	LINC00506 MIR4795 CHMP2B POU1F1 HTR1F VGLL3
nsv470749	Chr.3:87258397 - 87302230 on Build GRCh38	Loss	POU1F1

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
cell fate specification
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
positive regulation of cell proliferation
negative regulation of cell proliferation
determination of adult lifespan
B cell differentiation
positive regulation of inositol trisphosphate biosynthetic process
positive regulation of multicellular organism growth
regulation of insulin-like growth factor receptor signaling pathway
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
nuclear transport
somatotropin secreting cell development

Function(s)

RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
RNA polymerase II transcription factor binding
RNA polymerase II activating transcription factor binding
RNA polymerase II transcription coactivator activity
chromatin binding
transcription factor activity, sequence-specific DNA binding
transcription corepressor activity